Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083037072> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2083037072 endingPage "372" @default.
- W2083037072 startingPage "355" @default.
- W2083037072 abstract "Membrane preparations of collagenase-dispersed Langerhans islets of female Wistar rats exhibit specific binding sites for 125I labelled ovine prolactin (125I-oPrl). Almost negligible binding was detected in islets of male animals. The binding is a saturable and time-temperature dependent process, equilibrium being reached after 16 h incubation at 0°C. The bound oPrl is not displaceable by hFSH, hLH, bGH or hGH. In contrast with other cell fractions, the 12,000 g pellet accounts for more than 80% of the specific binding of 125I-oPrl. Scatchard plots of data obtained in saturation studies indicate a single class of binding sites with Ka = 0.21 × 1010 M-1. Protein and phospholipid moieties are essential for the receptor activity, since after trypsin or phospholipase C digestions marked loss of binding was verified. In islets of streptozotocin diabetic rats a marked reduction in the number of binding sites was observed. These findings may suggest that some of the actions of prolactin on endocrine pancreas could be explained by its specific interaction with islet cell membranes." @default.
- W2083037072 created "2016-06-24" @default.
- W2083037072 creator A5029833136 @default.
- W2083037072 creator A5045357881 @default.
- W2083037072 creator A5072043136 @default.
- W2083037072 date "1980-01-01" @default.
- W2083037072 modified "2023-10-15" @default.
- W2083037072 title "Proiactin Binding in Rat Langerhans Islets" @default.
- W2083037072 cites W106604922 @default.
- W2083037072 cites W1560521346 @default.
- W2083037072 cites W1775749144 @default.
- W2083037072 cites W1963563564 @default.
- W2083037072 cites W1970595886 @default.
- W2083037072 cites W1974955233 @default.
- W2083037072 cites W1981503997 @default.
- W2083037072 cites W1981640569 @default.
- W2083037072 cites W1983649348 @default.
- W2083037072 cites W1989745664 @default.
- W2083037072 cites W1992804332 @default.
- W2083037072 cites W1993673746 @default.
- W2083037072 cites W1997342108 @default.
- W2083037072 cites W2001692408 @default.
- W2083037072 cites W2017264854 @default.
- W2083037072 cites W2026358418 @default.
- W2083037072 cites W2045251608 @default.
- W2083037072 cites W2050951459 @default.
- W2083037072 cites W2051590554 @default.
- W2083037072 cites W2057818999 @default.
- W2083037072 cites W2084988392 @default.
- W2083037072 cites W2085810378 @default.
- W2083037072 cites W2086486141 @default.
- W2083037072 cites W2086739820 @default.
- W2083037072 cites W2157865424 @default.
- W2083037072 cites W2219872443 @default.
- W2083037072 cites W4255920682 @default.
- W2083037072 doi "https://doi.org/10.3109/10799898009038787" @default.
- W2083037072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6271957" @default.
- W2083037072 hasPublicationYear "1980" @default.
- W2083037072 type Work @default.
- W2083037072 sameAs 2083037072 @default.
- W2083037072 citedByCount "11" @default.
- W2083037072 countsByYear W20830370722014 @default.
- W2083037072 crossrefType "journal-article" @default.
- W2083037072 hasAuthorship W2083037072A5029833136 @default.
- W2083037072 hasAuthorship W2083037072A5045357881 @default.
- W2083037072 hasAuthorship W2083037072A5072043136 @default.
- W2083037072 hasConcept C107824862 @default.
- W2083037072 hasConcept C126322002 @default.
- W2083037072 hasConcept C134018914 @default.
- W2083037072 hasConcept C165220095 @default.
- W2083037072 hasConcept C170493617 @default.
- W2083037072 hasConcept C181199279 @default.
- W2083037072 hasConcept C185592680 @default.
- W2083037072 hasConcept C2778394429 @default.
- W2083037072 hasConcept C2779306644 @default.
- W2083037072 hasConcept C41625074 @default.
- W2083037072 hasConcept C55493867 @default.
- W2083037072 hasConcept C71924100 @default.
- W2083037072 hasConcept C86803240 @default.
- W2083037072 hasConceptScore W2083037072C107824862 @default.
- W2083037072 hasConceptScore W2083037072C126322002 @default.
- W2083037072 hasConceptScore W2083037072C134018914 @default.
- W2083037072 hasConceptScore W2083037072C165220095 @default.
- W2083037072 hasConceptScore W2083037072C170493617 @default.
- W2083037072 hasConceptScore W2083037072C181199279 @default.
- W2083037072 hasConceptScore W2083037072C185592680 @default.
- W2083037072 hasConceptScore W2083037072C2778394429 @default.
- W2083037072 hasConceptScore W2083037072C2779306644 @default.
- W2083037072 hasConceptScore W2083037072C41625074 @default.
- W2083037072 hasConceptScore W2083037072C55493867 @default.
- W2083037072 hasConceptScore W2083037072C71924100 @default.
- W2083037072 hasConceptScore W2083037072C86803240 @default.
- W2083037072 hasIssue "3" @default.
- W2083037072 hasLocation W20830370721 @default.
- W2083037072 hasLocation W20830370722 @default.
- W2083037072 hasOpenAccess W2083037072 @default.
- W2083037072 hasPrimaryLocation W20830370721 @default.
- W2083037072 hasRelatedWork W2022101623 @default.
- W2083037072 hasRelatedWork W2022911798 @default.
- W2083037072 hasRelatedWork W2049736637 @default.
- W2083037072 hasRelatedWork W2055682770 @default.
- W2083037072 hasRelatedWork W2069511360 @default.
- W2083037072 hasRelatedWork W2157325370 @default.
- W2083037072 hasRelatedWork W2164653018 @default.
- W2083037072 hasRelatedWork W2393326866 @default.
- W2083037072 hasRelatedWork W2528516704 @default.
- W2083037072 hasRelatedWork W2977378907 @default.
- W2083037072 hasVolume "1" @default.
- W2083037072 isParatext "false" @default.
- W2083037072 isRetracted "false" @default.
- W2083037072 magId "2083037072" @default.
- W2083037072 workType "article" @default.