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- W2083089734 abstract "Chronic idiopathic urticaria (CIU) is a common cutaneous disorder but the influence of initial treatment modality on long-term control is not known. The aim of this study was to evaluate clinical features, and the influence of initial treatment modality on long-term control.641 CIU patients were enrolled from the allergy clinic in a tertiary referral hospital. Disease duration, aggravating factors and treatment modality at each visit were evaluated. Times required to reach a controlled state were analyzed according to initial treatment modality, using Kaplan-Meier survival curves, the Cox proportional-hazards model, and propensity scores. Female to male ratio was 1.7: 1; mean age at onset was 40.5 years. The most common aggravating factors were food (33.5%), stress (31.5%) and fatigue (21.6%). Most patients (82.2%) used H1-antihistamines alone as initial treatment while 17% used a combination treatment with oral corticosteroids. There was no significant difference in the time taken to reach a controlled state between patients treated with single vs multiple H1-antihistamines or between those who received H1-antihistamine monotherapy vs. a combination therapy with oral corticosteroids.The time required to control CIU is not reduced by use of multiple H1-antihistamines or oral corticosteroids in the initial treatment." @default.
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- W2083089734 date "2013-07-23" @default.
- W2083089734 modified "2023-10-18" @default.
- W2083089734 title "Influence of Initial Treatment Modality on Long-Term Control of Chronic Idiopathic Urticaria" @default.
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- W2083089734 doi "https://doi.org/10.1371/journal.pone.0069345" @default.
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