FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083101222> ?p ?o ?g. }

• W2083101222 endingPage "21" @default.
• W2083101222 startingPage "21" @default.
• W2083101222 abstract "Monotherapy of androgen deprivation therapy versus radical prostatectomy among veterans with localized prostate cancer: comparative effectiveness analysis of retrospective cohorts Jinan Liu1,2, Lizheng Shi1,2,3, Oliver Sartor31Tulane University, School of Public Health and Tropical Medicine, 2Southeast Louisiana Veterans Health Care System, Tulane University, 3School of Medicine and Tulane Cancer Center, New Orleans, LA, USABackground: This retrospective cohort study aimed to examine the comparative effectiveness of monotherapy of primary androgen deprivation therapy or radical prostatectomy.Methods: Male patients with localized prostate cancer (T1-T2, N0, M0) were identified in the Veterans Affairs Veterans Integrated Service Network 16 data warehouse (January 2003 to June 2006), with one-year baseline and at least three-year follow-up data (until June 2009). Patients were required to be 18–75 years old and without other recorded cancer history. The initiation of primary androgen deprivation therapy or monotherapy of radical prostatectomy within six months after the first diagnosis of prostate cancer was used as the index date. Primary androgen deprivation therapy patients were matched to the radical prostatectomy patients via propensity score, which was predicted from a logistic regression of treatment selection (primary androgen deprivation therapy versus radical prostatectomy) on age, race, marital status, insurance type, cancer stage, Charlson comorbidity index, and alcohol and tobacco use. The overall survival from initiation of index treatment was then analyzed using the Kaplan–Meier and Cox proportional hazards model.Results: The two cohorts were well matched at baseline (all P > 0.05). During a median follow-up of 4.3 years, the cumulative incidence of death was 13 (10.57%) among 123 primary androgen deprivation therapy patients and four (3.25%) among 123 radical prostatectomy patients (P < 0.05). The overall three-year survival rate was 92.68% for primary androgen deprivation therapy and 98.37% for radical prostatectomy (P < 0.05). Patients who received primary androgen deprivation therapy had almost three times as high a mortality risk as those using radical prostatectomy (hazards ratio 3.388, 95% confidence interval 1.094–10.492, P = 0.034).Conclusion: After propensity score matching, overall three-year survival rate following radical prostatectomy among patients with localized prostate cancer was significantly higher than that after primary androgen deprivation therapy.Keywords: prostate cancer, primary androgen deprivation therapy, radical prostatectomy, survival rate" @default.
• W2083101222 created "2016-06-24" @default.
• W2083101222 creator A5033266357 @default.
• W2083101222 creator A5069523303 @default.
• W2083101222 creator A5073246821 @default.
• W2083101222 date "2012-05-01" @default.
• W2083101222 modified "2023-09-27" @default.
• W2083101222 title "Monotherapy of androgen deprivation therapy versus radical prostatectomy among veterans with localized prostate cancer: comparative effectiveness analysis of retrospective cohorts" @default.
• W2083101222 cites W1982473888 @default.
• W2083101222 cites W1983414502 @default.
• W2083101222 cites W1993746892 @default.
• W2083101222 cites W1997732940 @default.
• W2083101222 cites W2024785664 @default.
• W2083101222 cites W2065616395 @default.
• W2083101222 cites W2082371826 @default.
• W2083101222 cites W2098998490 @default.
• W2083101222 cites W2099145539 @default.
• W2083101222 cites W2101001966 @default.
• W2083101222 cites W2105877079 @default.
• W2083101222 cites W2106285196 @default.
• W2083101222 cites W2117511763 @default.
• W2083101222 cites W2125451496 @default.
• W2083101222 cites W2127088268 @default.
• W2083101222 cites W2132508160 @default.
• W2083101222 cites W2132935740 @default.
• W2083101222 cites W2142658264 @default.
• W2083101222 cites W2159805452 @default.
• W2083101222 cites W2160217483 @default.
• W2083101222 cites W2161964583 @default.
• W2083101222 cites W2316095838 @default.
• W2083101222 cites W2337912524 @default.
• W2083101222 cites W49263098 @default.
• W2083101222 cites W97172831 @default.
• W2083101222 doi "https://doi.org/10.2147/cer.s30024" @default.
• W2083101222 hasPublicationYear "2012" @default.
• W2083101222 type Work @default.
• W2083101222 sameAs 2083101222 @default.
• W2083101222 citedByCount "0" @default.
• W2083101222 crossrefType "journal-article" @default.
• W2083101222 hasAuthorship W2083101222A5033266357 @default.
• W2083101222 hasAuthorship W2083101222A5069523303 @default.
• W2083101222 hasAuthorship W2083101222A5073246821 @default.
• W2083101222 hasBestOaLocation W20831012221 @default.
• W2083101222 hasConcept C121608353 @default.
• W2083101222 hasConcept C126322002 @default.
• W2083101222 hasConcept C126894567 @default.
• W2083101222 hasConcept C143998085 @default.
• W2083101222 hasConcept C167135981 @default.
• W2083101222 hasConcept C2775969662 @default.
• W2083101222 hasConcept C2777899217 @default.
• W2083101222 hasConcept C2779466945 @default.
• W2083101222 hasConcept C2780192828 @default.
• W2083101222 hasConcept C29456083 @default.
• W2083101222 hasConcept C50382708 @default.
• W2083101222 hasConcept C71924100 @default.
• W2083101222 hasConcept C72563966 @default.
• W2083101222 hasConceptScore W2083101222C121608353 @default.
• W2083101222 hasConceptScore W2083101222C126322002 @default.
• W2083101222 hasConceptScore W2083101222C126894567 @default.
• W2083101222 hasConceptScore W2083101222C143998085 @default.
• W2083101222 hasConceptScore W2083101222C167135981 @default.
• W2083101222 hasConceptScore W2083101222C2775969662 @default.
• W2083101222 hasConceptScore W2083101222C2777899217 @default.
• W2083101222 hasConceptScore W2083101222C2779466945 @default.
• W2083101222 hasConceptScore W2083101222C2780192828 @default.
• W2083101222 hasConceptScore W2083101222C29456083 @default.
• W2083101222 hasConceptScore W2083101222C50382708 @default.
• W2083101222 hasConceptScore W2083101222C71924100 @default.
• W2083101222 hasConceptScore W2083101222C72563966 @default.
• W2083101222 hasLocation W20831012221 @default.
• W2083101222 hasOpenAccess W2083101222 @default.
• W2083101222 hasPrimaryLocation W20831012221 @default.
• W2083101222 hasRelatedWork W1760780539 @default.
• W2083101222 hasRelatedWork W2042143271 @default.
• W2083101222 hasRelatedWork W2044284566 @default.
• W2083101222 hasRelatedWork W2118670275 @default.
• W2083101222 hasRelatedWork W2402249956 @default.
• W2083101222 hasRelatedWork W2756688586 @default.
• W2083101222 hasRelatedWork W2904168711 @default.
• W2083101222 hasRelatedWork W4281959228 @default.
• W2083101222 hasRelatedWork W4307585143 @default.
• W2083101222 hasRelatedWork W4319748405 @default.
• W2083101222 isParatext "false" @default.
• W2083101222 isRetracted "false" @default.
• W2083101222 magId "2083101222" @default.
• W2083101222 workType "article" @default.