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• W2083103048 abstract "Peripheral serotonergic parameters were studied in 17 patients with a history of suicidal behavior and in 17 age- and sex-matched healthy controls. Serotonin2 receptor function in platelets, measured as serotonin-induced [32P]phosphatidylinositol 4,5-bisphosphate hydrolysis, was significantly higher in patients than in age- and sex-matched controls. Increased serotonin2 receptor transduction was not correlated to psychiatric diagnosis, drug treatment or a history of violent suicide attempt. Monoamine oxidase activity was lower in platelets from patients with a history of suicidal behavior than in controls. In addition, whole blood serotonin was analyzed but no significant alterations were found in blood from patients." @default.
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• W2083103048 date "1991-12-01" @default.
• W2083103048 modified "2023-10-18" @default.
• W2083103048 title "Peripheral serotonergic markers in patients with suicidal behavior" @default.
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• W2083103048 doi "https://doi.org/10.1016/0924-977x(91)90003-d" @default.
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