FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083132249> ?p ?o ?g. }

• W2083132249 endingPage "1365" @default.
• W2083132249 startingPage "1359" @default.
• W2083132249 abstract "Abstract: Compounds known to affect glycogen metabolism in vivo or in cell‐free preparations were used to investigate the regulation of glycogen content in intact astrocytes cultured from newborn rat cortex. Compounds were added with fresh medium to culture dishes, and astrocyte glucose and glycogen content determined 24 h later. Increasing the medium glucose concentration from 7.5 m M to 30 m M increased cell glycogen content 80%. Addition of 2‐deoxyglucose or 3‐ O ‐methyl glucose (2.5–10 m M ) also increased cell glycogen content, 50–100%, suggesting a regulatory rather than mass action effect of glucose on astrocyte glycogen content. The phosphorylase b inhibitors 2,2′,4,4′,5,5′‐hexabromobiphenyl and riboflavin had no effect on astrocyte glycogen content, consistent with negligible phosphorylase b activity in normal astrocytes. Phenobarbital and l ‐methionine‐DL‐sulfoximine (MSO) are both known to induce astrocyte glycogen accumulation in vivo. The addition of phenobarbital (2 m M ) had no effect on the glycogen content of cultured astrocytes, suggesting an indirect mechanism for the in vivo effect. MSO at 1 m M , however, induced a 300% increase in glycogen content. The time course of glucose and glycogen content after MSO administration suggests this increase to be the result of slowed glycogenolysis rather than accelerated glycogen synthesis." @default.
• W2083132249 created "2016-06-24" @default.
• W2083132249 creator A5005476873 @default.
• W2083132249 creator A5021502220 @default.
• W2083132249 creator A5022193976 @default.
• W2083132249 creator A5073936292 @default.
• W2083132249 date "1989-05-01" @default.
• W2083132249 modified "2023-10-16" @default.
• W2083132249 title "Regulation of Glycogen Content in Primary Astrocyte Culture: Effects of Glucose Analogues, Phenobarbital, and Methionine Sulfoximine" @default.
• W2083132249 cites W1560125983 @default.
• W2083132249 cites W1614353075 @default.
• W2083132249 cites W1775749144 @default.
• W2083132249 cites W1839389740 @default.
• W2083132249 cites W1975474858 @default.
• W2083132249 cites W1975628441 @default.
• W2083132249 cites W1979914485 @default.
• W2083132249 cites W1982868274 @default.
• W2083132249 cites W1984732016 @default.
• W2083132249 cites W1989775093 @default.
• W2083132249 cites W1992405727 @default.
• W2083132249 cites W1998179357 @default.
• W2083132249 cites W2013195856 @default.
• W2083132249 cites W2013387855 @default.
• W2083132249 cites W2016761017 @default.
• W2083132249 cites W2017653266 @default.
• W2083132249 cites W2027780701 @default.
• W2083132249 cites W2041257397 @default.
• W2083132249 cites W2043889745 @default.
• W2083132249 cites W2045949644 @default.
• W2083132249 cites W2048120082 @default.
• W2083132249 cites W2054235148 @default.
• W2083132249 cites W2055340924 @default.
• W2083132249 cites W2060148820 @default.
• W2083132249 cites W2062355127 @default.
• W2083132249 cites W2065225601 @default.
• W2083132249 cites W2070417335 @default.
• W2083132249 cites W2071578272 @default.
• W2083132249 cites W2074016932 @default.
• W2083132249 cites W2084380399 @default.
• W2083132249 cites W2090237801 @default.
• W2083132249 cites W2090673969 @default.
• W2083132249 cites W2093869236 @default.
• W2083132249 cites W2151913862 @default.
• W2083132249 cites W2154433130 @default.
• W2083132249 cites W4252976734 @default.
• W2083132249 doi "https://doi.org/10.1111/j.1471-4159.1989.tb09180.x" @default.
• W2083132249 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2540267" @default.
• W2083132249 hasPublicationYear "1989" @default.
• W2083132249 type Work @default.
• W2083132249 sameAs 2083132249 @default.
• W2083132249 citedByCount "68" @default.
• W2083132249 countsByYear W20831322492013 @default.
• W2083132249 countsByYear W20831322492014 @default.
• W2083132249 countsByYear W20831322492015 @default.
• W2083132249 countsByYear W20831322492019 @default.
• W2083132249 countsByYear W20831322492022 @default.
• W2083132249 countsByYear W20831322492023 @default.
• W2083132249 crossrefType "journal-article" @default.
• W2083132249 hasAuthorship W2083132249A5005476873 @default.
• W2083132249 hasAuthorship W2083132249A5021502220 @default.
• W2083132249 hasAuthorship W2083132249A5022193976 @default.
• W2083132249 hasAuthorship W2083132249A5073936292 @default.
• W2083132249 hasConcept C109384507 @default.
• W2083132249 hasConcept C126322002 @default.
• W2083132249 hasConcept C134018914 @default.
• W2083132249 hasConcept C150903083 @default.
• W2083132249 hasConcept C185592680 @default.
• W2083132249 hasConcept C192118531 @default.
• W2083132249 hasConcept C204779464 @default.
• W2083132249 hasConcept C207001950 @default.
• W2083132249 hasConcept C2777499176 @default.
• W2083132249 hasConcept C2777542381 @default.
• W2083132249 hasConcept C529278444 @default.
• W2083132249 hasConcept C55493867 @default.
• W2083132249 hasConcept C71924100 @default.
• W2083132249 hasConcept C86803240 @default.
• W2083132249 hasConcept C9262364 @default.
• W2083132249 hasConceptScore W2083132249C109384507 @default.
• W2083132249 hasConceptScore W2083132249C126322002 @default.
• W2083132249 hasConceptScore W2083132249C134018914 @default.
• W2083132249 hasConceptScore W2083132249C150903083 @default.
• W2083132249 hasConceptScore W2083132249C185592680 @default.
• W2083132249 hasConceptScore W2083132249C192118531 @default.
• W2083132249 hasConceptScore W2083132249C204779464 @default.
• W2083132249 hasConceptScore W2083132249C207001950 @default.
• W2083132249 hasConceptScore W2083132249C2777499176 @default.
• W2083132249 hasConceptScore W2083132249C2777542381 @default.
• W2083132249 hasConceptScore W2083132249C529278444 @default.
• W2083132249 hasConceptScore W2083132249C55493867 @default.
• W2083132249 hasConceptScore W2083132249C71924100 @default.
• W2083132249 hasConceptScore W2083132249C86803240 @default.
• W2083132249 hasConceptScore W2083132249C9262364 @default.
• W2083132249 hasIssue "5" @default.
• W2083132249 hasLocation W20831322491 @default.
• W2083132249 hasLocation W20831322492 @default.
• W2083132249 hasOpenAccess W2083132249 @default.
• W2083132249 hasPrimaryLocation W20831322491 @default.
• W2083132249 hasRelatedWork W1557918944 @default.

• next