FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083145327> ?p ?o ?g. }

• W2083145327 endingPage "482" @default.
• W2083145327 startingPage "467" @default.
• W2083145327 abstract "Bone loss due to congenital defects, trauma, improper fracture fixation, metabolic disturbances, infections, or after tumor resection represents a major clinical problem in head and neck surgery. To address these issues, different types of scaffolds, growth factors and cell sources -- alone or in various combinations -- have been applied for development of bioartificial bone tissues. Although these applications have received increasing interest, use of autologous bone grafts is still considered as the gold standard for tissue repair. Despite progress in some areas of tissue regeneration, significant translation into clinical practice has not been achieved. Reasons for this impass include rejection of engineered tissue implants by the immune system, limited blood supply, or morbidity of the donor site. During the process of bone regeneration, approximately 50-70% of osteoblasts undergo apoptosis. Apoptosis is a naturally occurring cell death pathway induced in a variety of cell types and is associated with caspase activation or caspase mediation. It is recognized as an important component of embryogenesis and tissue morphogenesis and, in adult skeletons, it contributes substantially to physiological bone turnover, repair, and regeneration. Intracellular mechanisms are orchestrated by a variety of proteins, the interplay of which seems to vary, depending on the differentiation state of the cell or the current status of the tissue. Closing gaps in current knowledge of the apoptosis of bone and understanding the mechanisms of cell death in tissue engineered bone will improve results in the translation from bench to bedsite. This review aims to provide a broad overview of the current general concepts in apoptosis with a special focus on its regulation in osteoblasts and its significance for bone tissue engineering." @default.
• W2083145327 created "2016-06-24" @default.
• W2083145327 creator A5001336776 @default.
• W2083145327 creator A5011254043 @default.
• W2083145327 creator A5030499700 @default.
• W2083145327 creator A5045121029 @default.
• W2083145327 creator A5063921909 @default.
• W2083145327 date "2008-07-01" @default.
• W2083145327 modified "2023-10-11" @default.
• W2083145327 title "Apoptosis in Bone for Tissue Engineering" @default.
• W2083145327 cites W107210068 @default.
• W2083145327 cites W1482449432 @default.
• W2083145327 cites W1483929886 @default.
• W2083145327 cites W1492606093 @default.
• W2083145327 cites W1573798987 @default.
• W2083145327 cites W1589415602 @default.
• W2083145327 cites W161342019 @default.
• W2083145327 cites W1701172542 @default.
• W2083145327 cites W1902976989 @default.
• W2083145327 cites W1964483580 @default.
• W2083145327 cites W1966223430 @default.
• W2083145327 cites W1967470081 @default.
• W2083145327 cites W1968694257 @default.
• W2083145327 cites W1968822620 @default.
• W2083145327 cites W1968837865 @default.
• W2083145327 cites W1969331809 @default.
• W2083145327 cites W1972211130 @default.
• W2083145327 cites W1973109581 @default.
• W2083145327 cites W1973436922 @default.
• W2083145327 cites W1974607378 @default.
• W2083145327 cites W1976570855 @default.
• W2083145327 cites W1977505218 @default.
• W2083145327 cites W1982769493 @default.
• W2083145327 cites W1982912854 @default.
• W2083145327 cites W1985712533 @default.
• W2083145327 cites W1987286030 @default.
• W2083145327 cites W1987386868 @default.
• W2083145327 cites W1991415492 @default.
• W2083145327 cites W1991830067 @default.
• W2083145327 cites W1992527837 @default.
• W2083145327 cites W1992695863 @default.
• W2083145327 cites W2002315967 @default.
• W2083145327 cites W2005950537 @default.
• W2083145327 cites W2006234957 @default.
• W2083145327 cites W2007057690 @default.
• W2083145327 cites W2007593446 @default.
• W2083145327 cites W2007901604 @default.
• W2083145327 cites W2008348103 @default.
• W2083145327 cites W2008376982 @default.
• W2083145327 cites W2010061535 @default.
• W2083145327 cites W2012173926 @default.
• W2083145327 cites W2012337697 @default.
• W2083145327 cites W2015032348 @default.
• W2083145327 cites W2017145829 @default.
• W2083145327 cites W2017293256 @default.
• W2083145327 cites W2017706980 @default.
• W2083145327 cites W2018190225 @default.
• W2083145327 cites W2019922960 @default.
• W2083145327 cites W2023845007 @default.
• W2083145327 cites W2024232113 @default.
• W2083145327 cites W2024445545 @default.
• W2083145327 cites W2027521516 @default.
• W2083145327 cites W2030450624 @default.
• W2083145327 cites W2032417513 @default.
• W2083145327 cites W2034213169 @default.
• W2083145327 cites W2035252337 @default.
• W2083145327 cites W2038118195 @default.
• W2083145327 cites W2041853090 @default.
• W2083145327 cites W2042409437 @default.
• W2083145327 cites W2046303644 @default.
• W2083145327 cites W2047717819 @default.
• W2083145327 cites W2050640903 @default.
• W2083145327 cites W2050866010 @default.
• W2083145327 cites W2051880245 @default.
• W2083145327 cites W2052232074 @default.
• W2083145327 cites W2052853635 @default.
• W2083145327 cites W2055580039 @default.
• W2083145327 cites W2059507366 @default.
• W2083145327 cites W2060279594 @default.
• W2083145327 cites W2060292345 @default.
• W2083145327 cites W2061497413 @default.
• W2083145327 cites W2065309389 @default.
• W2083145327 cites W2065345406 @default.
• W2083145327 cites W2065942289 @default.
• W2083145327 cites W2066789432 @default.
• W2083145327 cites W2067872631 @default.
• W2083145327 cites W2069707798 @default.
• W2083145327 cites W2074955580 @default.
• W2083145327 cites W2075292460 @default.
• W2083145327 cites W2083757029 @default.
• W2083145327 cites W2083906562 @default.
• W2083145327 cites W2085390592 @default.
• W2083145327 cites W2089174051 @default.
• W2083145327 cites W2089273654 @default.
• W2083145327 cites W2089947504 @default.
• W2083145327 cites W2091267060 @default.
• W2083145327 cites W2093101819 @default.
• W2083145327 cites W2098381715 @default.

• next