Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083150673> ?p ?o ?g. }
- W2083150673 endingPage "2461" @default.
- W2083150673 startingPage "2461" @default.
- W2083150673 abstract "Water accounts for about 60% of the human body. About a half of the remaining part consists of amino acids (including proteins). Amino acids are essential for nutrition and they work as hub compounds in metabolic pathways. Therefore, their concentrations in the biofluids could reflect various diseases (hepatocellular carcinoma, malignant melanoma, liver disease, coronary heart disease, rheumatoid arthritis, chronic renal failure, diabetes mellitus, Alzheimer's disease) and metabolic conditions. Especially, branched amino acids (BCAAs) are frequently affected. It is very important to analyze the concentration of BCAAs. The fruit fly, Drosophila melanogaster, is one of the most valuable organisms in biological research, particularly in genetics and developmental biology. Mutant flies, with defects in any of several thousand genes, are available, and the entire genome has been sequenced. The fly's genome is in good agreement with those of other eukaryotic organisms, including human. In the future, the fly will be used in other omics studies, such as metabolomics. However, since the fly is very small, it is quite difficult to analyze the metabolites in its body. To obtain an aminogram of the fly, a large sample pool is required. However, the pooled results can lead to the conclusion that the fly's aminogram is equalized, and the various important distinctions are lost. To address this issue, in this study, we have used a highly sensitive analytical method for a single fly sample. The method involves LC-ICP-MS after pre-column derivatization with a metal tag reagent. We could determine the quantities of free BCAAs in a single adult fly, the pupa, the larva and the ovary. In addition, we have found that the quantity of free BCAAs in the body of the mated female fly becomes increased." @default.
- W2083150673 created "2016-06-24" @default.
- W2083150673 creator A5002873416 @default.
- W2083150673 creator A5015223184 @default.
- W2083150673 creator A5038428640 @default.
- W2083150673 creator A5022787420 @default.
- W2083150673 date "2011-01-01" @default.
- W2083150673 modified "2023-09-26" @default.
- W2083150673 title "Quantitative analysis of branched amino acids in a single fruit fly by LC-ICP-MS after pre-column derivatization with a metal tag reagent" @default.
- W2083150673 cites W1895239351 @default.
- W2083150673 cites W1967168807 @default.
- W2083150673 cites W1976841916 @default.
- W2083150673 cites W1978992242 @default.
- W2083150673 cites W1983202741 @default.
- W2083150673 cites W1992939155 @default.
- W2083150673 cites W1993229728 @default.
- W2083150673 cites W2017470279 @default.
- W2083150673 cites W2018574489 @default.
- W2083150673 cites W2028875503 @default.
- W2083150673 cites W2038122931 @default.
- W2083150673 cites W2038144142 @default.
- W2083150673 cites W2041729711 @default.
- W2083150673 cites W2069236385 @default.
- W2083150673 cites W2071205437 @default.
- W2083150673 cites W2078061189 @default.
- W2083150673 cites W2088589804 @default.
- W2083150673 cites W2099203431 @default.
- W2083150673 cites W2106745511 @default.
- W2083150673 cites W2115432680 @default.
- W2083150673 cites W2131802378 @default.
- W2083150673 cites W2138167959 @default.
- W2083150673 cites W2141652419 @default.
- W2083150673 cites W2146128992 @default.
- W2083150673 cites W2150794901 @default.
- W2083150673 cites W2167481594 @default.
- W2083150673 cites W2264407089 @default.
- W2083150673 doi "https://doi.org/10.1039/c1ja10212e" @default.
- W2083150673 hasPublicationYear "2011" @default.
- W2083150673 type Work @default.
- W2083150673 sameAs 2083150673 @default.
- W2083150673 citedByCount "9" @default.
- W2083150673 countsByYear W20831506732012 @default.
- W2083150673 countsByYear W20831506732013 @default.
- W2083150673 countsByYear W20831506732014 @default.
- W2083150673 countsByYear W20831506732016 @default.
- W2083150673 countsByYear W20831506732017 @default.
- W2083150673 countsByYear W20831506732018 @default.
- W2083150673 countsByYear W20831506732021 @default.
- W2083150673 crossrefType "journal-article" @default.
- W2083150673 hasAuthorship W2083150673A5002873416 @default.
- W2083150673 hasAuthorship W2083150673A5015223184 @default.
- W2083150673 hasAuthorship W2083150673A5022787420 @default.
- W2083150673 hasAuthorship W2083150673A5038428640 @default.
- W2083150673 hasConcept C104317684 @default.
- W2083150673 hasConcept C178790620 @default.
- W2083150673 hasConcept C179998833 @default.
- W2083150673 hasConcept C181199279 @default.
- W2083150673 hasConcept C185592680 @default.
- W2083150673 hasConcept C2776041557 @default.
- W2083150673 hasConcept C2776923573 @default.
- W2083150673 hasConcept C2779201268 @default.
- W2083150673 hasConcept C2780104201 @default.
- W2083150673 hasConcept C40875361 @default.
- W2083150673 hasConcept C42407357 @default.
- W2083150673 hasConcept C43617362 @default.
- W2083150673 hasConcept C515207424 @default.
- W2083150673 hasConcept C55493867 @default.
- W2083150673 hasConcept C70721500 @default.
- W2083150673 hasConcept C86803240 @default.
- W2083150673 hasConceptScore W2083150673C104317684 @default.
- W2083150673 hasConceptScore W2083150673C178790620 @default.
- W2083150673 hasConceptScore W2083150673C179998833 @default.
- W2083150673 hasConceptScore W2083150673C181199279 @default.
- W2083150673 hasConceptScore W2083150673C185592680 @default.
- W2083150673 hasConceptScore W2083150673C2776041557 @default.
- W2083150673 hasConceptScore W2083150673C2776923573 @default.
- W2083150673 hasConceptScore W2083150673C2779201268 @default.
- W2083150673 hasConceptScore W2083150673C2780104201 @default.
- W2083150673 hasConceptScore W2083150673C40875361 @default.
- W2083150673 hasConceptScore W2083150673C42407357 @default.
- W2083150673 hasConceptScore W2083150673C43617362 @default.
- W2083150673 hasConceptScore W2083150673C515207424 @default.
- W2083150673 hasConceptScore W2083150673C55493867 @default.
- W2083150673 hasConceptScore W2083150673C70721500 @default.
- W2083150673 hasConceptScore W2083150673C86803240 @default.
- W2083150673 hasIssue "12" @default.
- W2083150673 hasLocation W20831506731 @default.
- W2083150673 hasOpenAccess W2083150673 @default.
- W2083150673 hasPrimaryLocation W20831506731 @default.
- W2083150673 hasRelatedWork W1968781128 @default.
- W2083150673 hasRelatedWork W1970143041 @default.
- W2083150673 hasRelatedWork W2008937680 @default.
- W2083150673 hasRelatedWork W2018569889 @default.
- W2083150673 hasRelatedWork W2026578023 @default.
- W2083150673 hasRelatedWork W2027971524 @default.
- W2083150673 hasRelatedWork W2036255866 @default.
- W2083150673 hasRelatedWork W2058020531 @default.
- W2083150673 hasRelatedWork W2089074688 @default.