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- W2083155814 abstract "The left ventricular pressure, arterial blood pressure and heart rate were studied in three series of pentobarbital-anaesthetized rats exposed to 5-bar normoxic (Po2= 0.2 bar) environments: nitrogen-oxygen (15 and 60 min) and helium-oxygen (15 min). The maximal left ventricular pressure (LVP max) and the maximal velocities of LVP rise (+ dP/dt max) and fall (- dP/dt) were significantly (P < 0.01) increased immediately after reaching normoxic 5 bar (He, 13–28%; N2, 13–23%) and during the exposure at 5 bar (He, 22–44%; N2, 13–18%). The pulse pressure increased significantly (He, 50–62%; N2, 30–34%; P 0.01) during the hyperbaric exposure. No changes in heart rate or end-diastolic and mean arterial pressure were detected. The present findings indicate an enhanced cardiac contractility (+ dP/dt max) at 5 bar, with the greatest increase found when He was used as inert gas. The increased contractility was of significant duration (at least 60 min), and was not completely-reversed until 5–10 min after decompression." @default.
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- W2083155814 date "1989-06-01" @default.
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- W2083155814 title "Increased cardiac contractility in rats exposed to 5 bar" @default.
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- W2083155814 doi "https://doi.org/10.1111/j.1748-1716.1989.tb08649.x" @default.
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