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- W2083178880 abstract "Permethylation of the glycan isolated from the glycoinositol phospholipid (GPI) anchor of the scrapie prion protein (PrPSc) trimethylates a free hexosamine to form a quarternary ammonium salt, substantially increasing the sensitivity for analysis by mass spectrometry. This derivatization induces specific fragmentation reactions in collision-induced dissociation spectra obtained on a four-sector tandem mass spectrometer, identifying the branching pattern of the PrPSc GPI glycan." @default.
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- W2083178880 date "1990-11-01" @default.
- W2083178880 modified "2023-10-17" @default.
- W2083178880 title "Permethylation and tandem mass spectrometry of oligosaccharides having free hexosamine: Analysis of the glycoinositol phospholipid anchor glycan from the scrapie prion protein" @default.
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- W2083178880 doi "https://doi.org/10.1016/0003-2697(90)90405-x" @default.
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