FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083183265> ?p ?o ?g. }

• W2083183265 endingPage "613" @default.
• W2083183265 startingPage "605" @default.
• W2083183265 abstract "Polysialic acid (polySia) is a functional epitope and is known: 1) to regulate normal fertilization of lower vertebrates and invertebrates; 2) to be expressed on neural cell adhesion molecule (NCAM) when the formation or re-arrangement of nervous tissues takes place during embryonic stages as well as in adults of higher vertebrates; and 3) to be re-expressed in several human tumors. Thus, polySia serves as oncodevelopmental antigen. To date sensitive biochemical diagnostic probes (antibodies and endo-N-acylneuraminidase) to detect polySia are known. However, these reagents are not commercially available yet and they are only reactive to specific types of polySia structure. Moreover, precise information not only on diversity but also on the length or degree of polymerization (DP) of extended polySia chains is considered important in understanding the molecular mechanism of biosynthesis of polySia chains and fine-tuning of NCAM-NCAM adhesive interaction by polySia chain but cannot be obtained with these biochemical probes. We have been continuously making efforts to develop and improve the sensitivity of chemical methods for polySia analysis toward these challenging problems. This article presents our most recently developed chemical method for polySia analysis and its use in obtaining new information on DP of colominic acid samples and polySia chains present in rat brain tissues with the highest sensitivity that has ever been attained." @default.
• W2083183265 created "2016-06-24" @default.
• W2083183265 creator A5030736937 @default.
• W2083183265 creator A5079718541 @default.
• W2083183265 date "2001-07-01" @default.
• W2083183265 modified "2023-09-27" @default.
• W2083183265 title "A challenge to the ultrasensitive chemical method for the analysis of oligo- and polysialic acids at a nanogram level of colominic acid and a milligram level of brain tissues" @default.
• W2083183265 cites W1487427036 @default.
• W2083183265 cites W1506739991 @default.
• W2083183265 cites W1507147440 @default.
• W2083183265 cites W1516244994 @default.
• W2083183265 cites W1516340190 @default.
• W2083183265 cites W1532606334 @default.
• W2083183265 cites W1535328119 @default.
• W2083183265 cites W1543366590 @default.
• W2083183265 cites W1571559460 @default.
• W2083183265 cites W1592948505 @default.
• W2083183265 cites W1604742230 @default.
• W2083183265 cites W1632209234 @default.
• W2083183265 cites W1901042123 @default.
• W2083183265 cites W1915391240 @default.
• W2083183265 cites W1964709514 @default.
• W2083183265 cites W1965569406 @default.
• W2083183265 cites W1967095650 @default.
• W2083183265 cites W1967160723 @default.
• W2083183265 cites W1967541644 @default.
• W2083183265 cites W1971396774 @default.
• W2083183265 cites W1986048273 @default.
• W2083183265 cites W1986285560 @default.
• W2083183265 cites W1992137936 @default.
• W2083183265 cites W1992304266 @default.
• W2083183265 cites W1998393573 @default.
• W2083183265 cites W2001782983 @default.
• W2083183265 cites W2002856175 @default.
• W2083183265 cites W2005854068 @default.
• W2083183265 cites W2014754929 @default.
• W2083183265 cites W2017726307 @default.
• W2083183265 cites W2018366006 @default.
• W2083183265 cites W2022752799 @default.
• W2083183265 cites W2030066690 @default.
• W2083183265 cites W2034918699 @default.
• W2083183265 cites W2044092574 @default.
• W2083183265 cites W2044237630 @default.
• W2083183265 cites W2044908499 @default.
• W2083183265 cites W2046203969 @default.
• W2083183265 cites W2048541390 @default.
• W2083183265 cites W2049723448 @default.
• W2083183265 cites W2053470401 @default.
• W2083183265 cites W2057241909 @default.
• W2083183265 cites W2059416563 @default.
• W2083183265 cites W2060271573 @default.
• W2083183265 cites W2060372519 @default.
• W2083183265 cites W2062989333 @default.
• W2083183265 cites W2067762612 @default.
• W2083183265 cites W2072577348 @default.
• W2083183265 cites W2072863903 @default.
• W2083183265 cites W2075777104 @default.
• W2083183265 cites W2078032475 @default.
• W2083183265 cites W2083743613 @default.
• W2083183265 cites W2085402247 @default.
• W2083183265 cites W2085680371 @default.
• W2083183265 cites W2091483994 @default.
• W2083183265 cites W2113624712 @default.
• W2083183265 cites W2146813978 @default.
• W2083183265 cites W2162186271 @default.
• W2083183265 cites W2166998993 @default.
• W2083183265 doi "https://doi.org/10.1016/s0300-9084(01)01307-4" @default.
• W2083183265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11522389" @default.
• W2083183265 hasPublicationYear "2001" @default.
• W2083183265 type Work @default.
• W2083183265 sameAs 2083183265 @default.
• W2083183265 citedByCount "23" @default.
• W2083183265 countsByYear W20831832652012 @default.
• W2083183265 countsByYear W20831832652013 @default.
• W2083183265 countsByYear W20831832652014 @default.
• W2083183265 countsByYear W20831832652019 @default.
• W2083183265 countsByYear W20831832652020 @default.
• W2083183265 countsByYear W20831832652021 @default.
• W2083183265 crossrefType "journal-article" @default.
• W2083183265 hasAuthorship W2083183265A5030736937 @default.
• W2083183265 hasAuthorship W2083183265A5079718541 @default.
• W2083183265 hasConcept C122871604 @default.
• W2083183265 hasConcept C147483822 @default.
• W2083183265 hasConcept C1491633281 @default.
• W2083183265 hasConcept C169760540 @default.
• W2083183265 hasConcept C185592680 @default.
• W2083183265 hasConcept C195616568 @default.
• W2083183265 hasConcept C203014093 @default.
• W2083183265 hasConcept C2778993516 @default.
• W2083183265 hasConcept C2986936838 @default.
• W2083183265 hasConcept C55493867 @default.
• W2083183265 hasConcept C85789140 @default.
• W2083183265 hasConcept C86803240 @default.
• W2083183265 hasConceptScore W2083183265C122871604 @default.
• W2083183265 hasConceptScore W2083183265C147483822 @default.
• W2083183265 hasConceptScore W2083183265C1491633281 @default.
• W2083183265 hasConceptScore W2083183265C169760540 @default.
• W2083183265 hasConceptScore W2083183265C185592680 @default.

• next