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• W2083202373 abstract "RNA interference or RNAi is an evolutionary-conserved mechanism present in virtually all eukaryotic cell. The process is triggered by the presence of double-stranded RNA (dsRNA), which is formed transiently during the replication of many viral genomes, but generally is absent from non-infected cells. Therefore, RNAi is believed to represent an ancestral form of nucleic acid based ‘immunity’ against intracellular pathogens resulting in a sequence-specific silencing of gene expression [1,2]. Gene silencing by RNAi involves the generation of short (21–23 nucleotide) duplex RNA species from a longer precursor by an endonuclease called ‘dicer’ [3]." @default.
• W2083202373 created "2016-06-24" @default.
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• W2083202373 date "2005-01-01" @default.
• W2083202373 modified "2023-09-25" @default.
• W2083202373 title "The potential of RNA interference as a tool in the management of viral hepatitis" @default.
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• W2083202373 doi "https://doi.org/10.1016/j.jhep.2004.10.022" @default.
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