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- W2083207745 endingPage "60" @default.
- W2083207745 startingPage "52" @default.
- W2083207745 abstract "Alcohol dehydrogenase (ADH) consists of a family of isozymes that convert alcohols to their corresponding aldehydes using NAD+ as a cofactor. The metabolism of ethanol by gastrointestinal ADH isozymes results in the production of acetaldehyde, a highly toxic compound that binds to cellular protein and DNA if not further metabolized to acetate by acetaldehyde dehydrogenase isozymes. Acetaldehyde seems to be involved in ethanol-associated cocarcinogenesis. The metabolism of retinol and the generation of retinoic acid is a function of class I and class IV ADH, and its inhibition by alcohol may lead to an alteration of epithelial cell differentiation and cell growth and may also be involved in ethanol-associated gastrointestinal cocarcinogenesis." @default.
- W2083207745 created "2016-06-24" @default.
- W2083207745 creator A5001762271 @default.
- W2083207745 creator A5021871537 @default.
- W2083207745 date "2009-04-27" @default.
- W2083207745 modified "2023-10-14" @default.
- W2083207745 title "Gastrointestinal Alcohol Dehydrogenase" @default.
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- W2083207745 cites W1500082482 @default.
- W2083207745 cites W1575798933 @default.
- W2083207745 cites W1606021311 @default.
- W2083207745 cites W162258464 @default.
- W2083207745 cites W1721799416 @default.
- W2083207745 cites W1790726923 @default.
- W2083207745 cites W1857381806 @default.
- W2083207745 cites W1864749219 @default.
- W2083207745 cites W1885597095 @default.
- W2083207745 cites W1891617153 @default.
- W2083207745 cites W1893989214 @default.
- W2083207745 cites W1923205770 @default.
- W2083207745 cites W1964460830 @default.
- W2083207745 cites W1965109741 @default.
- W2083207745 cites W1965977999 @default.
- W2083207745 cites W1968937339 @default.
- W2083207745 cites W1969475056 @default.
- W2083207745 cites W1969768788 @default.
- W2083207745 cites W1970747424 @default.
- W2083207745 cites W1975422271 @default.
- W2083207745 cites W1976289352 @default.
- W2083207745 cites W1977483712 @default.
- W2083207745 cites W1979322079 @default.
- W2083207745 cites W1980143759 @default.
- W2083207745 cites W1984562714 @default.
- W2083207745 cites W1984830140 @default.
- W2083207745 cites W1985791298 @default.
- W2083207745 cites W1995264623 @default.
- W2083207745 cites W1998329406 @default.
- W2083207745 cites W1998916013 @default.
- W2083207745 cites W1999401667 @default.
- W2083207745 cites W1999641310 @default.
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- W2083207745 cites W2003375846 @default.
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- W2083207745 cites W2009310386 @default.
- W2083207745 cites W2009477063 @default.
- W2083207745 cites W2014309091 @default.
- W2083207745 cites W2016976268 @default.
- W2083207745 cites W2022153378 @default.
- W2083207745 cites W2022757240 @default.
- W2083207745 cites W2023363028 @default.
- W2083207745 cites W2023614129 @default.
- W2083207745 cites W2031655347 @default.
- W2083207745 cites W2040193384 @default.
- W2083207745 cites W2041251771 @default.
- W2083207745 cites W2043700110 @default.
- W2083207745 cites W2048537862 @default.
- W2083207745 cites W2049087666 @default.
- W2083207745 cites W2062716859 @default.
- W2083207745 cites W2068525750 @default.
- W2083207745 cites W2077664624 @default.
- W2083207745 cites W2087596237 @default.
- W2083207745 cites W2092699918 @default.
- W2083207745 cites W2093537179 @default.
- W2083207745 cites W2097616503 @default.
- W2083207745 cites W2098334733 @default.
- W2083207745 cites W2103664025 @default.
- W2083207745 cites W2106794369 @default.
- W2083207745 cites W2107168553 @default.
- W2083207745 cites W2119294396 @default.
- W2083207745 cites W2127004748 @default.
- W2083207745 cites W2131630482 @default.
- W2083207745 cites W2131911594 @default.
- W2083207745 cites W2132978369 @default.
- W2083207745 cites W2142965797 @default.
- W2083207745 cites W2145998512 @default.
- W2083207745 cites W2149945265 @default.
- W2083207745 cites W2162958611 @default.
- W2083207745 cites W2324928881 @default.
- W2083207745 cites W2407982341 @default.
- W2083207745 cites W2955761657 @default.
- W2083207745 cites W4240369691 @default.
- W2083207745 doi "https://doi.org/10.1111/j.1753-4887.1998.tb01692.x" @default.
- W2083207745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9529900" @default.
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