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- W2083211557 abstract "Postmarketing reports indicate that use of the dipeptidyl peptidase-IV (DPP-IV) inhibitor sitagliptin can be associated with the development of serious hypersensitivity reactions including angioedema (1). The clinical characteristics of individuals who are prone to develop DPP-IV inhibitor–associated angioedema are not completely understood. Here, we report a case of sitagliptin-associated angioedema and suggest a potential role of angiotensin II receptor blocker (ARB) losartan in the development of the sitagliptin side effect.A 46-year-old African American female with a past medical history of uncomplicated hypertension treated with losartan 100-mg daily, obesity, and compensated vitamin D deficiency was referred to the endocrinology clinic by her internist for management of Riedel’s thyroiditis. Physical examination was significant for BMI of 35 kg/m2 and blood …" @default.
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- W2083211557 date "2012-07-14" @default.
- W2083211557 modified "2023-09-25" @default.
- W2083211557 title "Sitagliptin-Associated Angioedema" @default.
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- W2083211557 doi "https://doi.org/10.2337/dc12-0574" @default.
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