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- W2083222030 abstract "The low molecular weight RNAs in the nucleus and cytoplasm of mouse myeloma cells have been characterized. There are major nuclear species (other than 5-S and tRNA), four of which contain 'capped' 5' termini. There are three major small cytoplasmic RNAs none of which contain 'caps'. The biosynthesis of the nuclear species when studied using [3H]adenosine as an RNA precursor is characterized by a rapid, transient appearance in the cytoplasm, followed by fixation in the nucleus. Within 15 min, the amount in the cytoplasm has reached a steady-state level maintained for 60 min, while the accumulation in nuclei is linear after a short lag (less than 5 min). When biosynthesis is studied using [Me-3H]methionine as a precursor, much less labeled RNA is present in the cytoplasm, suggesting that methylation may immediately precede fixation into the nucleus." @default.
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- W2083222030 date "1978-12-01" @default.
- W2083222030 modified "2023-10-14" @default.
- W2083222030 title "Biosynthesis of low molecular weight RNA in mouse myeloma cells" @default.
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- W2083222030 doi "https://doi.org/10.1016/0005-2787(78)90307-6" @default.
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