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- W2083233295 abstract "discussed. Some cancers develop as cellular masses which displace normal fibrous tissue or stroma,yielding a net drop in scattering properties. Some cancer may be more fibrous than normal tissuesyielding a net increase in scattering. Cancers sometimes develop increased vascularity which yields anet increase in absorption. Another measure is fluorescence, either autofluorescence or dye-enhancedfluorescence. This paper considers the limits of resolution when optically characterizing a smallspherical object within a turbid tissue. The ability to discriminate a small object with a stronglyincreased absorption vs a larger object with a slight increase in absorption is tested, using frequency-domain light transport with 3-GHz modulation of the light source. The results suggest that an objectabouty 1/10 the size of the tissue within which it is embedded can be distinguished by a pair of" @default.
- W2083233295 created "2016-06-24" @default.
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- W2083233295 date "1995-04-12" @default.
- W2083233295 modified "2023-09-23" @default.
- W2083233295 title "Mechanisms and limits of contrast in optical imaging of cancer" @default.
- W2083233295 cites W1966411342 @default.
- W2083233295 doi "https://doi.org/10.1117/12.206808" @default.
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