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- W2083236579 abstract "In January this year, Geron Corporation (Menlo Park, CA, USA) boosted midwinter spirits by announcing that cellular immortality may at last be within reach (Science 1998; 279: 349–52). The Geron team had extended the lifespan of normal human foreskin fibroblasts and retinal pigment epithelial cells by genetically engineering the cells to express telomerase, an enzyme that protects chromosomal ends—telomeres—from fraying during cell division. Although most observers doubt that this work will lead to an extension of human lifespan, the finding opens up new therapeutic possibilities for tackling diseases of ageing and cancer." @default.
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- W2083236579 title "Telomeres: keys to senescence and cancer" @default.
- W2083236579 doi "https://doi.org/10.1016/s0140-6736(05)79136-4" @default.
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