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- W2083283319 abstract "Familial Mediterranean Fever (FMF) is the most common hereditary autoinflammatory syndrome affecting >10,000 people in Israel. FMF is caused by mutations in the MEFV gene, which encodes for the pyrin protein that is part of the inflammation complex that activates IL-1β. Evidence from case reports/series and one controlled study supports IL-1 blockage as a potential treatment for FMF. Canakinumab (CAN) is a selective fully human monoclonal anti-IL-1β antibody." @default.
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- W2083283319 date "2013-11-01" @default.
- W2083283319 modified "2023-09-24" @default.
- W2083283319 title "OR7-005 – Canakinumab in childhood colchicine resistant FMF" @default.
- W2083283319 doi "https://doi.org/10.1186/1546-0096-11-s1-a106" @default.
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