Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083350418> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2083350418 endingPage "429" @default.
- W2083350418 startingPage "413" @default.
- W2083350418 abstract "1. The continuation of our experiments with intradermal Type I pneumococcus infection in rabbits has furnished further evidence of the marked analogies between this condition and that of human lobar pneumonia. 2. It has been found that the amount of antiserum necessary for successful therapy increases as the disease progresses, and that this progression has a definite mathematical character. Such a condition, it seems, can only be caused by a progressive accumulation of some toxic or antagonistic substance, the exact nature of which is not known. 3. Various lots of antipneumococcus sera have been tested for their therapeutic properties. The results from seven such sera show that this therapeutic value does not parallel the mouse-protective value. It is suggested that the rabbit technic may prove useful for the routine comparison and standardization of antipneumococcus sera since it represents a simple method for determining that property for which the serum is to be utilized. 4. The effect of non-specific therapy in this condition has been determined to be a transient disappearance from the blood stream of circulating organisms. This result was obtained with such heterologous materials as normal horse serum and typhoid vaccine but not with the homologous normal rabbit serum. 5. Rabbits recovering from the intradermal disease without treatment or with such inadequate treatment that the disease runs its normal course, were shown to have a definite though not permanent immunity. Cases in which the disease had been arrested at 24 hours by effective therapy with heterologous immune serum showed no immunity after the early disappearance of the passively administered elements. Cases which were brought to early recovery with immune homologous serum did show a definite immunity comparable to that which was developed in other animals as the result of an untreated course of the disease. 6. The immunity conferred by single and multiple vaccination is reported. The possibility of the application of such methods in the pneumonias of man is discussed and a method for such an application is suggested." @default.
- W2083350418 created "2016-06-24" @default.
- W2083350418 creator A5042549897 @default.
- W2083350418 date "1928-09-01" @default.
- W2083350418 modified "2023-09-24" @default.
- W2083350418 title "FURTHER EXPERIMENTS WITH THE INTRADERMAL PNEUMOCOCCUS INFECTION IN RABBITS" @default.
- W2083350418 doi "https://doi.org/10.1084/jem.48.3.413" @default.
- W2083350418 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2131476" @default.
- W2083350418 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19869495" @default.
- W2083350418 hasPublicationYear "1928" @default.
- W2083350418 type Work @default.
- W2083350418 sameAs 2083350418 @default.
- W2083350418 citedByCount "22" @default.
- W2083350418 crossrefType "journal-article" @default.
- W2083350418 hasAuthorship W2083350418A5042549897 @default.
- W2083350418 hasBestOaLocation W20833504181 @default.
- W2083350418 hasConcept C104317684 @default.
- W2083350418 hasConcept C126322002 @default.
- W2083350418 hasConcept C142724271 @default.
- W2083350418 hasConcept C147483822 @default.
- W2083350418 hasConcept C203014093 @default.
- W2083350418 hasConcept C2777914695 @default.
- W2083350418 hasConcept C2778937273 @default.
- W2083350418 hasConcept C2779134260 @default.
- W2083350418 hasConcept C2779341262 @default.
- W2083350418 hasConcept C2780115692 @default.
- W2083350418 hasConcept C55493867 @default.
- W2083350418 hasConcept C71924100 @default.
- W2083350418 hasConcept C86803240 @default.
- W2083350418 hasConcept C8891405 @default.
- W2083350418 hasConcept C91523082 @default.
- W2083350418 hasConceptScore W2083350418C104317684 @default.
- W2083350418 hasConceptScore W2083350418C126322002 @default.
- W2083350418 hasConceptScore W2083350418C142724271 @default.
- W2083350418 hasConceptScore W2083350418C147483822 @default.
- W2083350418 hasConceptScore W2083350418C203014093 @default.
- W2083350418 hasConceptScore W2083350418C2777914695 @default.
- W2083350418 hasConceptScore W2083350418C2778937273 @default.
- W2083350418 hasConceptScore W2083350418C2779134260 @default.
- W2083350418 hasConceptScore W2083350418C2779341262 @default.
- W2083350418 hasConceptScore W2083350418C2780115692 @default.
- W2083350418 hasConceptScore W2083350418C55493867 @default.
- W2083350418 hasConceptScore W2083350418C71924100 @default.
- W2083350418 hasConceptScore W2083350418C86803240 @default.
- W2083350418 hasConceptScore W2083350418C8891405 @default.
- W2083350418 hasConceptScore W2083350418C91523082 @default.
- W2083350418 hasIssue "3" @default.
- W2083350418 hasLocation W20833504181 @default.
- W2083350418 hasLocation W20833504182 @default.
- W2083350418 hasLocation W20833504183 @default.
- W2083350418 hasLocation W20833504184 @default.
- W2083350418 hasOpenAccess W2083350418 @default.
- W2083350418 hasPrimaryLocation W20833504181 @default.
- W2083350418 hasRelatedWork W1971546590 @default.
- W2083350418 hasRelatedWork W1993827401 @default.
- W2083350418 hasRelatedWork W2078952439 @default.
- W2083350418 hasRelatedWork W2101443423 @default.
- W2083350418 hasRelatedWork W2169743616 @default.
- W2083350418 hasRelatedWork W2220102944 @default.
- W2083350418 hasRelatedWork W2317169137 @default.
- W2083350418 hasRelatedWork W2409271623 @default.
- W2083350418 hasRelatedWork W257463849 @default.
- W2083350418 hasRelatedWork W4313309237 @default.
- W2083350418 hasVolume "48" @default.
- W2083350418 isParatext "false" @default.
- W2083350418 isRetracted "false" @default.
- W2083350418 magId "2083350418" @default.
- W2083350418 workType "article" @default.