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• W2083368916 abstract "The present study reports regression of pre-established experimental rat gliomas as a result of combining peripheral immunization using interferon gamma (IFNgamma) transduced autologous tumor cells with local intratumoral delivery of interleukin 7 (IL-7) by mesenchymal stromal cells. IL-7 alone significantly decreased the tumor area and this effect was enhanced with IFNgamma immunization. A higher density of intratumoral T-cells was observed in animals receiving combined therapies compared to rats receiving either cytokine alone suggesting that the therapeutic effect is dependent on a T-cell response." @default.
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• W2083368916 date "2010-01-01" @default.
• W2083368916 modified "2023-10-03" @default.
• W2083368916 title "Intratumoral IL-7 delivery by mesenchymal stromal cells potentiates IFNγ-transduced tumor cell immunotherapy of experimental glioma" @default.
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• W2083368916 doi "https://doi.org/10.1016/j.jneuroim.2009.10.017" @default.
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