Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083388500> ?p ?o ?g. }
- W2083388500 endingPage "478" @default.
- W2083388500 startingPage "471" @default.
- W2083388500 abstract "Abstract Complement has been studied for over a century and its role in promoting the effector side of antibody‐mediated immune reactions and of inducing inflammation is well understood. Nevertheless, it has proved surprisingly difficult to translate this information into pharmaceutical agents that can be used to treat immunopathological and inflammatory disease. There are, however, now clear signs that this situation will change. New types of therapeutic agents to interfere with complement function are being developed and it has become apparent quite recently that some common and otherwise untreatable diseases such as age‐related macular degeneration are very largely due to mutations in the complement system that leads to a hyperinflammatory state. This has stimulated a renaissance of interest in the complement system as a therapeutic target and in this short review we discuss the possible ways of taking complement to the clinic, and the indications for which this may be carried out." @default.
- W2083388500 created "2016-06-24" @default.
- W2083388500 creator A5015981919 @default.
- W2083388500 creator A5074196179 @default.
- W2083388500 date "2009-04-24" @default.
- W2083388500 modified "2023-10-16" @default.
- W2083388500 title "Taking Complement to the Clinic - has the Time Finally Come?" @default.
- W2083388500 cites W1568092328 @default.
- W2083388500 cites W1580446023 @default.
- W2083388500 cites W1585631706 @default.
- W2083388500 cites W1587809300 @default.
- W2083388500 cites W1963544181 @default.
- W2083388500 cites W1965855950 @default.
- W2083388500 cites W1966465960 @default.
- W2083388500 cites W1970232820 @default.
- W2083388500 cites W1975834355 @default.
- W2083388500 cites W1989716037 @default.
- W2083388500 cites W1993444676 @default.
- W2083388500 cites W1994366393 @default.
- W2083388500 cites W1998406682 @default.
- W2083388500 cites W1999844587 @default.
- W2083388500 cites W2002967092 @default.
- W2083388500 cites W2004265876 @default.
- W2083388500 cites W2007705388 @default.
- W2083388500 cites W2007907509 @default.
- W2083388500 cites W2008349565 @default.
- W2083388500 cites W2009601168 @default.
- W2083388500 cites W2013804060 @default.
- W2083388500 cites W2014418919 @default.
- W2083388500 cites W2019861301 @default.
- W2083388500 cites W2022763040 @default.
- W2083388500 cites W2023653161 @default.
- W2083388500 cites W2025189810 @default.
- W2083388500 cites W2039925500 @default.
- W2083388500 cites W2041834228 @default.
- W2083388500 cites W2041887649 @default.
- W2083388500 cites W2043095586 @default.
- W2083388500 cites W2043167284 @default.
- W2083388500 cites W2049102738 @default.
- W2083388500 cites W2055439322 @default.
- W2083388500 cites W2060977228 @default.
- W2083388500 cites W2062558590 @default.
- W2083388500 cites W2065803824 @default.
- W2083388500 cites W2067278353 @default.
- W2083388500 cites W2071087316 @default.
- W2083388500 cites W2071177681 @default.
- W2083388500 cites W2080829361 @default.
- W2083388500 cites W2083866706 @default.
- W2083388500 cites W2084186081 @default.
- W2083388500 cites W2090551909 @default.
- W2083388500 cites W2091933198 @default.
- W2083388500 cites W2092666893 @default.
- W2083388500 cites W2099248196 @default.
- W2083388500 cites W2105479207 @default.
- W2083388500 cites W2107283032 @default.
- W2083388500 cites W2109847629 @default.
- W2083388500 cites W2111733466 @default.
- W2083388500 cites W2127321441 @default.
- W2083388500 cites W2130696459 @default.
- W2083388500 cites W2144737888 @default.
- W2083388500 cites W2152757679 @default.
- W2083388500 cites W2158981826 @default.
- W2083388500 cites W2334940563 @default.
- W2083388500 doi "https://doi.org/10.1111/j.1365-3083.2009.02258.x" @default.
- W2083388500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19439007" @default.
- W2083388500 hasPublicationYear "2009" @default.
- W2083388500 type Work @default.
- W2083388500 sameAs 2083388500 @default.
- W2083388500 citedByCount "29" @default.
- W2083388500 countsByYear W20833885002012 @default.
- W2083388500 countsByYear W20833885002013 @default.
- W2083388500 countsByYear W20833885002014 @default.
- W2083388500 countsByYear W20833885002015 @default.
- W2083388500 countsByYear W20833885002016 @default.
- W2083388500 countsByYear W20833885002017 @default.
- W2083388500 countsByYear W20833885002018 @default.
- W2083388500 countsByYear W20833885002019 @default.
- W2083388500 countsByYear W20833885002022 @default.
- W2083388500 crossrefType "journal-article" @default.
- W2083388500 hasAuthorship W2083388500A5015981919 @default.
- W2083388500 hasAuthorship W2083388500A5074196179 @default.
- W2083388500 hasBestOaLocation W20833885001 @default.
- W2083388500 hasConcept C104317684 @default.
- W2083388500 hasConcept C111684460 @default.
- W2083388500 hasConcept C112313634 @default.
- W2083388500 hasConcept C127716648 @default.
- W2083388500 hasConcept C142724271 @default.
- W2083388500 hasConcept C188082640 @default.
- W2083388500 hasConcept C203014093 @default.
- W2083388500 hasConcept C2776914184 @default.
- W2083388500 hasConcept C2779134260 @default.
- W2083388500 hasConcept C51785407 @default.
- W2083388500 hasConcept C52069626 @default.
- W2083388500 hasConcept C52119013 @default.
- W2083388500 hasConcept C54355233 @default.
- W2083388500 hasConcept C71924100 @default.
- W2083388500 hasConcept C86803240 @default.
- W2083388500 hasConcept C8891405 @default.