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- W2083393253 abstract "22q11.2 deletion syndrome (22q11DS) is a neurogenetic syndrome associated with a high rate of psychiatric disorders. Previous research has revealed distinctive cognitive deficits, including impaired face processing. However, the neuro-functional substrates underlying these deficits have not been explored. Our aim was to investigate facial and emotional processing in 22q11DS.During event-related functional magnetic resonance imaging, 15 individuals with 22q11DS were compared with age- and gender-matched healthy control subjects on a simple visual categorization task (faces or houses). Each stimulus was presented twice, and faces had either neutral or emotional (fearful) expressions.Abnormal responses to faces were observed in 22q11DS, including a lack of normal face-selectivity in fusiform gyrus. By contrast, responses to houses were comparable across groups, with preserved selectivity in parahippocampal gyrus. Results also revealed a repetition-suppression effect for fearful faces in the right amygdala, which arose in healthy control subjects only, suggesting a lack of amygdala modulation by fear expression in 22q11DS.Our results demonstrate selective anomalies in several brain regions critically implicated in visual and social function in 22q11DS. These findings suggest important new avenues for studying emotional processing and social deficits frequently observed in psychotic patients and establishing their relation to specific phenotypic manifestations in 22q11DS." @default.
- W2083393253 created "2016-06-24" @default.
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- W2083393253 date "2008-01-01" @default.
- W2083393253 modified "2023-10-17" @default.
- W2083393253 title "Impaired Activation of Face Processing Networks Revealed by Functional Magnetic Resonance Imaging in 22q11.2 Deletion Syndrome" @default.
- W2083393253 cites W1522065225 @default.
- W2083393253 cites W1665095741 @default.
- W2083393253 cites W1873033581 @default.
- W2083393253 cites W1965960584 @default.
- W2083393253 cites W1969242329 @default.
- W2083393253 cites W1974572323 @default.
- W2083393253 cites W1978130180 @default.
- W2083393253 cites W1980446013 @default.
- W2083393253 cites W1980776446 @default.
- W2083393253 cites W1985940580 @default.
- W2083393253 cites W1986638206 @default.
- W2083393253 cites W1987599891 @default.
- W2083393253 cites W1991926550 @default.
- W2083393253 cites W1997927507 @default.
- W2083393253 cites W1999903950 @default.
- W2083393253 cites W2001977453 @default.
- W2083393253 cites W2007055606 @default.
- W2083393253 cites W2007062612 @default.
- W2083393253 cites W2012139659 @default.
- W2083393253 cites W2021591609 @default.
- W2083393253 cites W2024062662 @default.
- W2083393253 cites W2030234237 @default.
- W2083393253 cites W2035518691 @default.
- W2083393253 cites W2038394911 @default.
- W2083393253 cites W2040186606 @default.
- W2083393253 cites W2040394901 @default.
- W2083393253 cites W2044618620 @default.
- W2083393253 cites W2044952535 @default.
- W2083393253 cites W2045409727 @default.
- W2083393253 cites W2053519201 @default.
- W2083393253 cites W2054240744 @default.
- W2083393253 cites W2056435351 @default.
- W2083393253 cites W2065429082 @default.
- W2083393253 cites W2075341242 @default.
- W2083393253 cites W2075519476 @default.
- W2083393253 cites W2085383383 @default.
- W2083393253 cites W2086260743 @default.
- W2083393253 cites W2090144378 @default.
- W2083393253 cites W2101622575 @default.
- W2083393253 cites W2101763099 @default.
- W2083393253 cites W2101790396 @default.
- W2083393253 cites W2107932899 @default.
- W2083393253 cites W2113820953 @default.
- W2083393253 cites W2115933524 @default.
- W2083393253 cites W2119629804 @default.
- W2083393253 cites W2121876127 @default.
- W2083393253 cites W2123341385 @default.
- W2083393253 cites W2124807472 @default.
- W2083393253 cites W2125935651 @default.
- W2083393253 cites W2132934054 @default.
- W2083393253 cites W2133174477 @default.
- W2083393253 cites W2137483563 @default.
- W2083393253 cites W2138223873 @default.
- W2083393253 cites W2141012240 @default.
- W2083393253 cites W2141704087 @default.
- W2083393253 cites W2144906195 @default.
- W2083393253 cites W2147202753 @default.
- W2083393253 cites W2150959782 @default.
- W2083393253 cites W2151786648 @default.
- W2083393253 cites W2151915433 @default.
- W2083393253 cites W2154734566 @default.
- W2083393253 cites W2158327447 @default.
- W2083393253 cites W2158370744 @default.
- W2083393253 cites W2158553737 @default.
- W2083393253 cites W2163266267 @default.
- W2083393253 cites W2163471335 @default.
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- W2083393253 doi "https://doi.org/10.1016/j.biopsych.2007.02.022" @default.
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