FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083470141> ?p ?o ?g. }

• W2083470141 endingPage "41" @default.
• W2083470141 startingPage "33" @default.
• W2083470141 abstract "Peripheral blood lymphocytes from two polytransfused renal dialysis patients were transformed by Epstein Barr virus, fused to heteromyeloma and cloned. Eight human monoclonal antibodies from the resulting clones were tested for their binding to variety of antigens by ELISA, indirect immunofluorescence and immunoblotting. Antigens tested included B-cell lines, T and B lymphocytes, red blood cells, chronic lymphocytic leukaemic B cells, IgG, ssDNA, dsDNA. histones, nucleoprotamine, sperm nuclei, thymus and spleen extracts. MOLT4 cell lysatcs, affinity purified autoantigens, tetanus toxoid, bacterial lipopolysaccharide, insulin, and tissue section screen. These human monoclonal antibodies reacted with more than one antigen to varying degrees and were autoreactive and pulyreactive. One of these heterohybridoma cell lines exhibited cytoplasmic staining with an anti-CD5 monoclonal. Our findings support the concept that in adult individuals subset of B cells produce heterogeneous IgM antibodies which can bind to variety of different autoantigens and also to foreign antigens. These monoclonals were different from the autoantibodies usually seen in renal dialysis patients in the sense that they were not lymphocytotoxic." @default.
• W2083470141 created "2016-06-24" @default.
• W2083470141 creator A5018923494 @default.
• W2083470141 creator A5026650840 @default.
• W2083470141 creator A5027308727 @default.
• W2083470141 creator A5037629472 @default.
• W2083470141 creator A5041717462 @default.
• W2083470141 creator A5052961405 @default.
• W2083470141 creator A5079304212 @default.
• W2083470141 creator A5087369536 @default.
• W2083470141 date "1992-01-01" @default.
• W2083470141 modified "2023-10-17" @default.
• W2083470141 title "Production of Heterohybridomas Secreting Autoreactive and Polyreactive Human Monoclonal Antibodies" @default.
• W2083470141 cites W1033266375 @default.
• W2083470141 cites W1509021113 @default.
• W2083470141 cites W1624366049 @default.
• W2083470141 cites W1966844155 @default.
• W2083470141 cites W1968981783 @default.
• W2083470141 cites W1973170041 @default.
• W2083470141 cites W1976232165 @default.
• W2083470141 cites W1977721756 @default.
• W2083470141 cites W1981327412 @default.
• W2083470141 cites W1989725875 @default.
• W2083470141 cites W1990222908 @default.
• W2083470141 cites W2001863306 @default.
• W2083470141 cites W2004054985 @default.
• W2083470141 cites W2034515222 @default.
• W2083470141 cites W2043288877 @default.
• W2083470141 cites W2088468634 @default.
• W2083470141 cites W2100837269 @default.
• W2083470141 cites W2101108802 @default.
• W2083470141 cites W2105441566 @default.
• W2083470141 cites W2113980965 @default.
• W2083470141 cites W2118210213 @default.
• W2083470141 cites W2132024750 @default.
• W2083470141 cites W2167477934 @default.
• W2083470141 cites W2413873230 @default.
• W2083470141 cites W4241550322 @default.
• W2083470141 doi "https://doi.org/10.1111/j.1365-3083.1992.tb02831.x" @default.
• W2083470141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1734494" @default.
• W2083470141 hasPublicationYear "1992" @default.
• W2083470141 type Work @default.
• W2083470141 sameAs 2083470141 @default.
• W2083470141 citedByCount "9" @default.
• W2083470141 countsByYear W20834701412013 @default.
• W2083470141 crossrefType "journal-article" @default.
• W2083470141 hasAuthorship W2083470141A5018923494 @default.
• W2083470141 hasAuthorship W2083470141A5026650840 @default.
• W2083470141 hasAuthorship W2083470141A5027308727 @default.
• W2083470141 hasAuthorship W2083470141A5037629472 @default.
• W2083470141 hasAuthorship W2083470141A5041717462 @default.
• W2083470141 hasAuthorship W2083470141A5052961405 @default.
• W2083470141 hasAuthorship W2083470141A5079304212 @default.
• W2083470141 hasAuthorship W2083470141A5087369536 @default.
• W2083470141 hasConcept C113067387 @default.
• W2083470141 hasConcept C147483822 @default.
• W2083470141 hasConcept C153911025 @default.
• W2083470141 hasConcept C159047783 @default.
• W2083470141 hasConcept C159654299 @default.
• W2083470141 hasConcept C163864487 @default.
• W2083470141 hasConcept C195616568 @default.
• W2083470141 hasConcept C203014093 @default.
• W2083470141 hasConcept C2777351567 @default.
• W2083470141 hasConcept C2780801004 @default.
• W2083470141 hasConcept C2780931953 @default.
• W2083470141 hasConcept C542903549 @default.
• W2083470141 hasConcept C86803240 @default.
• W2083470141 hasConceptScore W2083470141C113067387 @default.
• W2083470141 hasConceptScore W2083470141C147483822 @default.
• W2083470141 hasConceptScore W2083470141C153911025 @default.
• W2083470141 hasConceptScore W2083470141C159047783 @default.
• W2083470141 hasConceptScore W2083470141C159654299 @default.
• W2083470141 hasConceptScore W2083470141C163864487 @default.
• W2083470141 hasConceptScore W2083470141C195616568 @default.
• W2083470141 hasConceptScore W2083470141C203014093 @default.
• W2083470141 hasConceptScore W2083470141C2777351567 @default.
• W2083470141 hasConceptScore W2083470141C2780801004 @default.
• W2083470141 hasConceptScore W2083470141C2780931953 @default.
• W2083470141 hasConceptScore W2083470141C542903549 @default.
• W2083470141 hasConceptScore W2083470141C86803240 @default.
• W2083470141 hasIssue "1" @default.
• W2083470141 hasLocation W20834701411 @default.
• W2083470141 hasLocation W20834701412 @default.
• W2083470141 hasOpenAccess W2083470141 @default.
• W2083470141 hasPrimaryLocation W20834701411 @default.
• W2083470141 hasRelatedWork W1604248381 @default.
• W2083470141 hasRelatedWork W1853117060 @default.
• W2083470141 hasRelatedWork W1997716688 @default.
• W2083470141 hasRelatedWork W2000527901 @default.
• W2083470141 hasRelatedWork W2071136098 @default.
• W2083470141 hasRelatedWork W2091594406 @default.
• W2083470141 hasRelatedWork W2417465673 @default.
• W2083470141 hasRelatedWork W4239344034 @default.
• W2083470141 hasRelatedWork W4241939667 @default.
• W2083470141 hasRelatedWork W4252441337 @default.
• W2083470141 hasVolume "35" @default.
• W2083470141 isParatext "false" @default.
• W2083470141 isRetracted "false" @default.

• next