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• W2083474469 abstract "Radiation-sensitive hydrogels offer the capability of verifying intricate dose distributions in three-dimensional (3D) space conveniently in a single measurement with sub-millimetre spatial resolution. In this study, a new radiochromic hydrogel called leuco crystal violet (LCV) micelle gel is introduced. Upon irradiation, LCV converts to crystal violet (CV(+)). Triton X-100 micelles are used to provide the required hybrid-interfacing environment to dissolve LCV. The diffusion coefficient of the LCV gel has been measured to be 0.036 +/- 0.001 mm(2) h(-1), which is a factor of 25 times less than the standard radiochromic ferrous xylenol-orange (FX) gel; LCV gels without Triton X-100 micelles have a diffusion coefficient of 0.33 +/- 0.02 mm(2) h(-1). The LCV gel formulation contains: 1 mM LCV, 25 mM trichloroacetic acid, 4 mM Triton X-100 and 4% w/w gelatin. The primary innovative feature of this 3D hydrogel is that the radiation-induced CV(+) dye is more soluble in the Triton X-100 micelles than in the surrounding water which consequently leads to more stable post-irradiation dose distributions. A dosimetric characterization revealed that the dose response is reproducible to within 1% over three separate batches, independent of energy, dose rate and dose fractionation but is affected by the temperature ( approximately 4% per degree C) during irradiation. LCV micelle gels scanned optically with a yellow light source are a promising system for 3D dose verification. They may prove to be, especially, useful for scanning large volume dosimeters (i.e. 20 cm) since they are easily manufactured, transparent and near colourless prior to irradiation." @default.
• W2083474469 created "2016-06-24" @default.
• W2083474469 creator A5020035172 @default.
• W2083474469 creator A5028474874 @default.
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• W2083474469 date "2009-10-21" @default.
• W2083474469 modified "2023-09-30" @default.
• W2083474469 title "Radiochromic leuco dye micelle hydrogels: II. Low diffusion rate leuco crystal violet gel" @default.
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• W2083474469 doi "https://doi.org/10.1088/0031-9155/54/22/003" @default.
• W2083474469 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19847015" @default.
• W2083474469 hasPublicationYear "2009" @default.
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