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- W2083486660 abstract "The absorption and degradation rates of 131I-labeled triiodothyronine (T3) were measured in human subjects by the whole-body counting methods previously described for 131I-thyroxine (T4). Results obtained in 18 euthyroid subjects were as follows: (a) There was a significant difference in the ratio of 0- and 4-hr counting sensitivity of T3 as compared with T4, suggesting significantly different spatial redistribution of T3 and T4 in the whole body during this time. (b) The variation in T3 counting sensitivity related to body weight was similar to that found with T4. (c) An average of 85% of an oral dose of T3 was found to be absorbed, (d) The T3 degradation rate was similar after oral and intravenous administration. However, after oral administration a significant time delay was observed before apparent degradation of T3 began. This has been attributed to temporary hepatic sequestration of the oral dose. (e) Fecal excretion of the administered T3 label (mean 10.4%) and fecal lag time (1.3 days) were simila..." @default.
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- W2083486660 date "1964-08-01" @default.
- W2083486660 modified "2023-09-27" @default.
- W2083486660 title "Whole-Body Counting of131I-Labeled Triiodothyronine" @default.
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- W2083486660 doi "https://doi.org/10.1210/jcem-24-8-733" @default.
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