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- W2083533104 abstract "Three new glycosylated phenazine derivatives, named izuminosides A–C (1–3) have been isolated from the ethyl acetate extract of Streptomyces sp. IFM 11260. The structures of the new compounds were determined on the basis of their spectral data. Compounds 1–3 were evaluated for their activity in overcoming tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) resistance in human gastric adenocarcinoma cells. Compounds 2 (10 μM) and 3 (60 μM) in combination with TRAIL showed synergistic activity in sensitizing TRAIL-resistance AGS cells." @default.
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- W2083533104 date "2011-02-09" @default.
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- W2083533104 title "Isolation and structure elucidation of izuminosides A–C: a rare phenazine glycosides from Streptomyces sp. IFM 11260" @default.
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- W2083533104 doi "https://doi.org/10.1038/ja.2010.172" @default.
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