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- W2083550489 abstract "The present study was carried out to evaluate the in vitro effects of mammalian gonadotropin-releasing hormone (mGnRH) on the production of prostaglandin F2 alpha (PGF2 alpha) and sex steroids (progesterone, androgens, and 17 beta-estradiol) by the interrenal gland of male and female Rana esculenta during three different periods of the sexual annual cycle. In both sexes, mGnRH induced a significant increase in PGF2 alpha in the incubation medium in all examined periods. Progesterone and androgens were undetectable, while 17 beta-estradiol was significantly increased by mGnRH in interrenals incubated during the postreproductive period in both sexes. These results suggest that R. esculenta interrenals could be a GnRH-dependent PGF2 alpha-secreting tissue. In addition, the simultaneous increase in PGF2 alpha and estradiol from postreproductive cultured interrenals support the notion that mGnRH-induced estradiol synthesis is mediated through PGF2 alpha formation. This finding, taken together with other previous studies, strongly suggests that the end of the breeding period in R. esculenta depends on GnRH-induced PGF2 alpha-mediated enhancement of estradiol synthesis in a steroidogenetic organ (probably interrenals)." @default.
- W2083550489 created "2016-06-24" @default.
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- W2083550489 date "1991-12-01" @default.
- W2083550489 modified "2023-10-03" @default.
- W2083550489 title "Gonadotropin-releasing hormone stimulates biosynthesis of prostaglandin F2α by the interrenal gland of the water frog, Rana esculenta, in vitro" @default.
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- W2083550489 doi "https://doi.org/10.1016/0016-6480(91)90092-k" @default.
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