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- W2083561231 abstract "Abstract Palm vitee was tested for acute toxicity in young albino mice and Sprague-Dawley rats. The animals were fed daily doses (250, 500, 1000 or 2500mg/kg) of palm vitee in refined, bleached and deodorized olein for 30 days. Time-matched controls consisted of untreated or olein-treated animals. Results indicated that treated rodents did not exhibit any physical abnormalities or unusual behaviour. However, some sluggish motor activity was manifested. Interestingly, treated mice gained weight significantly whereas treated rats grew normally over the 30-day period. In anaesthetized cats, palm vitee produced inconsistent, minor fluctuations in the mean arterial pressure and heart rate, but variable responses were also obtained with injections of olein alone. We concluded that palm vitee, in extremely high doses, did not appear to produce appreciable adverse effects in the animals used." @default.
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- W2083561231 date "1992-01-01" @default.
- W2083561231 modified "2023-09-24" @default.
- W2083561231 title "Toxicological and pharmacological studies on palm vitee" @default.
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- W2083561231 doi "https://doi.org/10.1016/s0271-5317(05)80465-8" @default.
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