FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083585822> ?p ?o ?g. }

• W2083585822 endingPage "172" @default.
• W2083585822 startingPage "165" @default.
• W2083585822 abstract "Abstract Posttranslational activation of nitrate reductase (NR) in Arabidopsis (Arabidopsis thaliana) and other higher plants is mediated by dephosphorylation at a specific Ser residue in the hinge between the molybdenum cofactor and heme-binding domains. The activation of NR in green leaves takes place after dark/light shifts, and is dependent on photosynthesis. Previous studies using various inhibitors pointed to protein phosphatases sensitive to okadaic acid, including protein phosphatase 2A (PP2A), as candidates for activation of NR. PP2As are heterotrimeric enzymes consisting of a catalytic (C), structural (A), and regulatory (B) subunit. In Arabidopsis there are five, three, and 18 of these subunits, respectively. By using inducible artificial microRNA to simultaneously knock down the three structural subunits we show that PP2A is necessary for NR activation. The structural subunits revealed overlapping functions in the activation process of NR. Bimolecular fluorescence complementation was used to identify PP2A regulatory subunits interacting with NR, and the two B55 subunits were positive. Interactions of NR and B55 were further confirmed by the yeast two-hybrid assay. In Arabidopsis the B55 group consists of the close homologs B55α and B55β. Interestingly, the homozygous double mutant (b55α × b55β) appeared to be lethal, which shows that the B55 group has essential functions that cannot be replaced by other regulatory subunits. Mutants homozygous for mutation in Bβ and heterozygous for mutation in Bα revealed a slower activation rate for NR than wild-type plants, pointing to these subunits as part of a PP2A complex responsible for NR dephosphorylation." @default.
• W2083585822 created "2016-06-24" @default.
• W2083585822 creator A5020931376 @default.
• W2083585822 creator A5032101621 @default.
• W2083585822 creator A5035968909 @default.
• W2083585822 creator A5046084258 @default.
• W2083585822 creator A5057931071 @default.
• W2083585822 creator A5061137627 @default.
• W2083585822 creator A5066353656 @default.
• W2083585822 date "2011-03-24" @default.
• W2083585822 modified "2023-09-23" @default.
• W2083585822 title "Protein Phosphatase 2A B55 and A Regulatory Subunits Interact with Nitrate Reductase and Are Essential for Nitrate Reductase Activation " @default.
• W2083585822 cites W1514640654 @default.
• W2083585822 cites W1540424041 @default.
• W2083585822 cites W1559869345 @default.
• W2083585822 cites W1571523637 @default.
• W2083585822 cites W1965169361 @default.
• W2083585822 cites W1982136041 @default.
• W2083585822 cites W1987093345 @default.
• W2083585822 cites W1992868294 @default.
• W2083585822 cites W1999793253 @default.
• W2083585822 cites W2003880331 @default.
• W2083585822 cites W2020223662 @default.
• W2083585822 cites W2027112332 @default.
• W2083585822 cites W2036825181 @default.
• W2083585822 cites W2038942260 @default.
• W2083585822 cites W2054525322 @default.
• W2083585822 cites W2057945816 @default.
• W2083585822 cites W2060770087 @default.
• W2083585822 cites W2074102891 @default.
• W2083585822 cites W2078918550 @default.
• W2083585822 cites W2084573676 @default.
• W2083585822 cites W2096183596 @default.
• W2083585822 cites W2097653436 @default.
• W2083585822 cites W2098115340 @default.
• W2083585822 cites W2104069743 @default.
• W2083585822 cites W2106488895 @default.
• W2083585822 cites W2107830697 @default.
• W2083585822 cites W2110333928 @default.
• W2083585822 cites W2114610097 @default.
• W2083585822 cites W2116266192 @default.
• W2083585822 cites W2117386768 @default.
• W2083585822 cites W2117682970 @default.
• W2083585822 cites W2118950779 @default.
• W2083585822 cites W2122511951 @default.
• W2083585822 cites W2140773448 @default.
• W2083585822 cites W2147036063 @default.
• W2083585822 cites W2147725450 @default.
• W2083585822 cites W2152732341 @default.
• W2083585822 cites W2156012113 @default.
• W2083585822 cites W2162177539 @default.
• W2083585822 cites W2165421630 @default.
• W2083585822 cites W2170164520 @default.
• W2083585822 doi "https://doi.org/10.1104/pp.111.172734" @default.
• W2083585822 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3091043" @default.
• W2083585822 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21436382" @default.
• W2083585822 hasPublicationYear "2011" @default.
• W2083585822 type Work @default.
• W2083585822 sameAs 2083585822 @default.
• W2083585822 citedByCount "60" @default.
• W2083585822 countsByYear W20835858222012 @default.
• W2083585822 countsByYear W20835858222013 @default.
• W2083585822 countsByYear W20835858222014 @default.
• W2083585822 countsByYear W20835858222015 @default.
• W2083585822 countsByYear W20835858222016 @default.
• W2083585822 countsByYear W20835858222017 @default.
• W2083585822 countsByYear W20835858222018 @default.
• W2083585822 countsByYear W20835858222019 @default.
• W2083585822 countsByYear W20835858222020 @default.
• W2083585822 countsByYear W20835858222021 @default.
• W2083585822 countsByYear W20835858222022 @default.
• W2083585822 countsByYear W20835858222023 @default.
• W2083585822 crossrefType "journal-article" @default.
• W2083585822 hasAuthorship W2083585822A5020931376 @default.
• W2083585822 hasAuthorship W2083585822A5032101621 @default.
• W2083585822 hasAuthorship W2083585822A5035968909 @default.
• W2083585822 hasAuthorship W2083585822A5046084258 @default.
• W2083585822 hasAuthorship W2083585822A5057931071 @default.
• W2083585822 hasAuthorship W2083585822A5061137627 @default.
• W2083585822 hasAuthorship W2083585822A5066353656 @default.
• W2083585822 hasBestOaLocation W20835858221 @default.
• W2083585822 hasConcept C104292427 @default.
• W2083585822 hasConcept C104317684 @default.
• W2083585822 hasConcept C115867849 @default.
• W2083585822 hasConcept C11960822 @default.
• W2083585822 hasConcept C123243835 @default.
• W2083585822 hasConcept C139407321 @default.
• W2083585822 hasConcept C143065580 @default.
• W2083585822 hasConcept C178666793 @default.
• W2083585822 hasConcept C181199279 @default.
• W2083585822 hasConcept C181912034 @default.
• W2083585822 hasConcept C188082640 @default.
• W2083585822 hasConcept C2775988993 @default.
• W2083585822 hasConcept C2778710519 @default.
• W2083585822 hasConcept C2779222958 @default.
• W2083585822 hasConcept C2779491563 @default.
• W2083585822 hasConcept C389152 @default.
• W2083585822 hasConcept C55493867 @default.

• next