Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083600527> ?p ?o ?g. }
- W2083600527 endingPage "94" @default.
- W2083600527 startingPage "90" @default.
- W2083600527 abstract "In vitro generation of red blood cells (RBC) makes sense in a context of recurrent shortage. It could be an interesting complementary source for classic transfusion products by combining the sufficiency of supply, homemade production of a particular phenotype of interest and reduced risk of infection. The question that arises is how to produce in vitro RBC? Here we retrace the steps that led to the production of functional RBC, from basic knowledge of in vivo erythropoiesis to in vitro generation of RBC from different sources of stem cells. Regarding the adults HSC, the major finding lies in the recent establishment of proof of concept of their transfusion in humans. Because the induced pluripotent stem cells (IPS) can proliferate indefinitely and be selected for a phenotype of interest, they are obviously the best source of stem cells. Proof of concept of generation of RBC from IPS has been made, but still has to be optimized. We also discuss the key points that need to be solved to achieve clinical transfusion application." @default.
- W2083600527 created "2016-06-24" @default.
- W2083600527 creator A5030064985 @default.
- W2083600527 creator A5077513049 @default.
- W2083600527 date "2013-05-01" @default.
- W2083600527 modified "2023-10-01" @default.
- W2083600527 title "Production de globules rouges dans un but transfusionnel ou l’itinéraire ex vivo d’une cellule souche" @default.
- W2083600527 cites W116951826 @default.
- W2083600527 cites W1516165231 @default.
- W2083600527 cites W1703848171 @default.
- W2083600527 cites W1779822690 @default.
- W2083600527 cites W1792460785 @default.
- W2083600527 cites W1915536483 @default.
- W2083600527 cites W1967521279 @default.
- W2083600527 cites W1968430274 @default.
- W2083600527 cites W1969483592 @default.
- W2083600527 cites W1970095666 @default.
- W2083600527 cites W1984271653 @default.
- W2083600527 cites W1990767607 @default.
- W2083600527 cites W1995509779 @default.
- W2083600527 cites W2001293440 @default.
- W2083600527 cites W2023559972 @default.
- W2083600527 cites W2033737798 @default.
- W2083600527 cites W2043247638 @default.
- W2083600527 cites W2055350454 @default.
- W2083600527 cites W2056574386 @default.
- W2083600527 cites W2058322611 @default.
- W2083600527 cites W2062201720 @default.
- W2083600527 cites W2062254735 @default.
- W2083600527 cites W2065314181 @default.
- W2083600527 cites W2067663452 @default.
- W2083600527 cites W2072990456 @default.
- W2083600527 cites W2077487953 @default.
- W2083600527 cites W2082915580 @default.
- W2083600527 cites W2088537786 @default.
- W2083600527 cites W2099697301 @default.
- W2083600527 cites W2125987139 @default.
- W2083600527 cites W2127088990 @default.
- W2083600527 cites W2140717627 @default.
- W2083600527 cites W2147032364 @default.
- W2083600527 cites W2156538246 @default.
- W2083600527 cites W2165494690 @default.
- W2083600527 cites W2166862788 @default.
- W2083600527 cites W2255192868 @default.
- W2083600527 cites W2265597917 @default.
- W2083600527 cites W2335969897 @default.
- W2083600527 cites W2409554838 @default.
- W2083600527 cites W2411181032 @default.
- W2083600527 cites W2413702326 @default.
- W2083600527 cites W307574227 @default.
- W2083600527 cites W86169078 @default.
- W2083600527 cites W2093202161 @default.
- W2083600527 cites W2139064256 @default.
- W2083600527 doi "https://doi.org/10.1016/j.tracli.2013.02.020" @default.
- W2083600527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23601197" @default.
- W2083600527 hasPublicationYear "2013" @default.
- W2083600527 type Work @default.
- W2083600527 sameAs 2083600527 @default.
- W2083600527 citedByCount "0" @default.
- W2083600527 crossrefType "journal-article" @default.
- W2083600527 hasAuthorship W2083600527A5030064985 @default.
- W2083600527 hasAuthorship W2083600527A5077513049 @default.
- W2083600527 hasConcept C104317684 @default.
- W2083600527 hasConcept C105580179 @default.
- W2083600527 hasConcept C126322002 @default.
- W2083600527 hasConcept C138885662 @default.
- W2083600527 hasConcept C150903083 @default.
- W2083600527 hasConcept C151730666 @default.
- W2083600527 hasConcept C153911025 @default.
- W2083600527 hasConcept C194051981 @default.
- W2083600527 hasConcept C203014093 @default.
- W2083600527 hasConcept C207001950 @default.
- W2083600527 hasConcept C26291073 @default.
- W2083600527 hasConcept C2778137410 @default.
- W2083600527 hasConcept C2778248108 @default.
- W2083600527 hasConcept C2778403015 @default.
- W2083600527 hasConcept C2779343474 @default.
- W2083600527 hasConcept C2779703530 @default.
- W2083600527 hasConcept C2780014101 @default.
- W2083600527 hasConcept C28328180 @default.
- W2083600527 hasConcept C41895202 @default.
- W2083600527 hasConcept C54355233 @default.
- W2083600527 hasConcept C71924100 @default.
- W2083600527 hasConcept C79592252 @default.
- W2083600527 hasConcept C86803240 @default.
- W2083600527 hasConcept C95444343 @default.
- W2083600527 hasConceptScore W2083600527C104317684 @default.
- W2083600527 hasConceptScore W2083600527C105580179 @default.
- W2083600527 hasConceptScore W2083600527C126322002 @default.
- W2083600527 hasConceptScore W2083600527C138885662 @default.
- W2083600527 hasConceptScore W2083600527C150903083 @default.
- W2083600527 hasConceptScore W2083600527C151730666 @default.
- W2083600527 hasConceptScore W2083600527C153911025 @default.
- W2083600527 hasConceptScore W2083600527C194051981 @default.
- W2083600527 hasConceptScore W2083600527C203014093 @default.
- W2083600527 hasConceptScore W2083600527C207001950 @default.
- W2083600527 hasConceptScore W2083600527C26291073 @default.
- W2083600527 hasConceptScore W2083600527C2778137410 @default.