Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083604263> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2083604263 endingPage "172" @default.
- W2083604263 startingPage "168" @default.
- W2083604263 abstract "Although mostly epidemiological studies suggested that carbon disulfide produces cardiovascular effects in occupationally exposed workers, little is known about its cellular mechanism. The purpose of the present study was to evaluate the functional and histological effects on cardiac myocytes cultured under the condition of carbon disulfide exposure. Cardiac myocytes were isolated from neonatal rat ventricles by trypsin dispersion and cultured for 3 days in a full (Dulbecco's modified eagle medium) medium containing 2% calf serum. Thereafter the myocytes (10(6) myocytes/culture flask) were incubated with carbon disulfide at (CS(2)) the concentrations of 0, 20, 40, and 80 micromol/mL) for 24h. The beating arrest rate of myocytes for each group was examined and succinodehydrogenase (SDH) activity in the myocardial cells was also assessed by cytochemical method, and morphological examination was also performed. We found that the beating arrest rate of cardiac myocytes increased with increasing exposure levels. Vacuolization and pseudopodia may be seen in the cytoplasm of exposure group. SDH activity decreased with increasing exposure levels. The results suggested that CS(2) has a direct cytotoxic effect which is dose dependent. The biochemical mechanism may be a reduction of the availability of energy of the cardiac cytocyte in the form of ATP, resulting in a decrease of contractility by lacking of energy." @default.
- W2083604263 created "2016-06-24" @default.
- W2083604263 creator A5001660299 @default.
- W2083604263 creator A5001979626 @default.
- W2083604263 creator A5028173735 @default.
- W2083604263 creator A5045960451 @default.
- W2083604263 creator A5068477746 @default.
- W2083604263 creator A5090798311 @default.
- W2083604263 date "2003-06-01" @default.
- W2083604263 modified "2023-10-18" @default.
- W2083604263 title "Carbon disulfide cytotoxicity on cultured cardiac myocyte cell of rats" @default.
- W2083604263 cites W1964741453 @default.
- W2083604263 cites W2049323215 @default.
- W2083604263 cites W2060349845 @default.
- W2083604263 cites W2080559175 @default.
- W2083604263 cites W2125454893 @default.
- W2083604263 cites W2159329277 @default.
- W2083604263 cites W2215510318 @default.
- W2083604263 cites W2401656144 @default.
- W2083604263 cites W2402071090 @default.
- W2083604263 cites W2404383542 @default.
- W2083604263 cites W2419339704 @default.
- W2083604263 cites W2436396369 @default.
- W2083604263 cites W2486900254 @default.
- W2083604263 doi "https://doi.org/10.1016/s0147-6513(02)00124-0" @default.
- W2083604263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12742364" @default.
- W2083604263 hasPublicationYear "2003" @default.
- W2083604263 type Work @default.
- W2083604263 sameAs 2083604263 @default.
- W2083604263 citedByCount "6" @default.
- W2083604263 countsByYear W20836042632015 @default.
- W2083604263 countsByYear W20836042632016 @default.
- W2083604263 countsByYear W20836042632019 @default.
- W2083604263 countsByYear W20836042632020 @default.
- W2083604263 countsByYear W20836042632023 @default.
- W2083604263 crossrefType "journal-article" @default.
- W2083604263 hasAuthorship W2083604263A5001660299 @default.
- W2083604263 hasAuthorship W2083604263A5001979626 @default.
- W2083604263 hasAuthorship W2083604263A5028173735 @default.
- W2083604263 hasAuthorship W2083604263A5045960451 @default.
- W2083604263 hasAuthorship W2083604263A5068477746 @default.
- W2083604263 hasAuthorship W2083604263A5090798311 @default.
- W2083604263 hasConcept C126322002 @default.
- W2083604263 hasConcept C134018914 @default.
- W2083604263 hasConcept C178790620 @default.
- W2083604263 hasConcept C185592680 @default.
- W2083604263 hasConcept C207200792 @default.
- W2083604263 hasConcept C2778614373 @default.
- W2083604263 hasConcept C2779607818 @default.
- W2083604263 hasConcept C3018686881 @default.
- W2083604263 hasConcept C39133596 @default.
- W2083604263 hasConcept C71924100 @default.
- W2083604263 hasConcept C86803240 @default.
- W2083604263 hasConceptScore W2083604263C126322002 @default.
- W2083604263 hasConceptScore W2083604263C134018914 @default.
- W2083604263 hasConceptScore W2083604263C178790620 @default.
- W2083604263 hasConceptScore W2083604263C185592680 @default.
- W2083604263 hasConceptScore W2083604263C207200792 @default.
- W2083604263 hasConceptScore W2083604263C2778614373 @default.
- W2083604263 hasConceptScore W2083604263C2779607818 @default.
- W2083604263 hasConceptScore W2083604263C3018686881 @default.
- W2083604263 hasConceptScore W2083604263C39133596 @default.
- W2083604263 hasConceptScore W2083604263C71924100 @default.
- W2083604263 hasConceptScore W2083604263C86803240 @default.
- W2083604263 hasIssue "2" @default.
- W2083604263 hasLocation W20836042631 @default.
- W2083604263 hasLocation W20836042632 @default.
- W2083604263 hasOpenAccess W2083604263 @default.
- W2083604263 hasPrimaryLocation W20836042631 @default.
- W2083604263 hasRelatedWork W1514902666 @default.
- W2083604263 hasRelatedWork W1987726533 @default.
- W2083604263 hasRelatedWork W1999008705 @default.
- W2083604263 hasRelatedWork W2037829466 @default.
- W2083604263 hasRelatedWork W2077755216 @default.
- W2083604263 hasRelatedWork W2083604263 @default.
- W2083604263 hasRelatedWork W2100071717 @default.
- W2083604263 hasRelatedWork W2114671826 @default.
- W2083604263 hasRelatedWork W2364509524 @default.
- W2083604263 hasRelatedWork W44147402 @default.
- W2083604263 hasVolume "55" @default.
- W2083604263 isParatext "false" @default.
- W2083604263 isRetracted "false" @default.
- W2083604263 magId "2083604263" @default.
- W2083604263 workType "article" @default.