Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083624877> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2083624877 endingPage "278" @default.
- W2083624877 startingPage "271" @default.
- W2083624877 abstract "The effects of administration of estradiol-17β on the activity of phosphohexose isomerase have been studied in the rat uterus. In ovariectomized rats, the activity of uterine phosphohexose isomerase was decreased to 49 per cent when compared to that of normal, unoperated rats. A single injection of estradiol-17β caused a marked increase in the enzyme activity which was detectable in 4 hours (153 per cent) and reached a maximum level (246 per cent) 16 hours after administration of the hormone. Dose-response studies indicated that was sufficient to induce a statistically significant increase in uterine phosphohexose isomerase activity (158 per cent). Enzyme activity was maximally elevated to 278 per cent with the dose. Treatment of estradiol injected rats with actinomycin, puromycin or ethionine, inhibitors of RNA and protein synthesis, completely blocked the estradiol-induced increase in the activity of uterine phosphohexose isomerase. Methionine, given concurrently with ethionine caused a complete reversal of ethionine inhibition of estradiol-induced rise in phosphohexose isomerase activity. The results suggest that the estradiol-induced increase in uterine phosphohexose isomerase activity represents enzyme biosynthesis de novo. The data are discussed in the light of current views regarding biochemical mechanisms underlying estrogenic action in the rat uterus." @default.
- W2083624877 created "2016-06-24" @default.
- W2083624877 creator A5003177026 @default.
- W2083624877 creator A5011279450 @default.
- W2083624877 creator A5021783558 @default.
- W2083624877 date "1967-03-01" @default.
- W2083624877 modified "2023-10-01" @default.
- W2083624877 title "Estrogen-induced increase in phosphohexose isomerase activity in the rat uterus" @default.
- W2083624877 cites W1418022162 @default.
- W2083624877 cites W1537643311 @default.
- W2083624877 cites W1604649689 @default.
- W2083624877 cites W1758315017 @default.
- W2083624877 cites W1969264878 @default.
- W2083624877 cites W1974810500 @default.
- W2083624877 cites W1991148666 @default.
- W2083624877 cites W1995697285 @default.
- W2083624877 cites W2003786239 @default.
- W2083624877 cites W2003880285 @default.
- W2083624877 cites W2011382641 @default.
- W2083624877 cites W2018949657 @default.
- W2083624877 cites W2037527944 @default.
- W2083624877 cites W2041256543 @default.
- W2083624877 cites W2072226999 @default.
- W2083624877 cites W2088296385 @default.
- W2083624877 cites W2093937313 @default.
- W2083624877 cites W2275268112 @default.
- W2083624877 cites W2425562674 @default.
- W2083624877 cites W2439819703 @default.
- W2083624877 cites W37533403 @default.
- W2083624877 doi "https://doi.org/10.1016/0026-0495(67)90176-x" @default.
- W2083624877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6020735" @default.
- W2083624877 hasPublicationYear "1967" @default.
- W2083624877 type Work @default.
- W2083624877 sameAs 2083624877 @default.
- W2083624877 citedByCount "12" @default.
- W2083624877 crossrefType "journal-article" @default.
- W2083624877 hasAuthorship W2083624877A5003177026 @default.
- W2083624877 hasAuthorship W2083624877A5011279450 @default.
- W2083624877 hasAuthorship W2083624877A5021783558 @default.
- W2083624877 hasConcept C126322002 @default.
- W2083624877 hasConcept C134018914 @default.
- W2083624877 hasConcept C181199279 @default.
- W2083624877 hasConcept C185592680 @default.
- W2083624877 hasConcept C2777164284 @default.
- W2083624877 hasConcept C2779066055 @default.
- W2083624877 hasConcept C2780486903 @default.
- W2083624877 hasConcept C2780912031 @default.
- W2083624877 hasConcept C28212737 @default.
- W2083624877 hasConcept C515207424 @default.
- W2083624877 hasConcept C55493867 @default.
- W2083624877 hasConcept C71924100 @default.
- W2083624877 hasConcept C8264082 @default.
- W2083624877 hasConcept C88189869 @default.
- W2083624877 hasConceptScore W2083624877C126322002 @default.
- W2083624877 hasConceptScore W2083624877C134018914 @default.
- W2083624877 hasConceptScore W2083624877C181199279 @default.
- W2083624877 hasConceptScore W2083624877C185592680 @default.
- W2083624877 hasConceptScore W2083624877C2777164284 @default.
- W2083624877 hasConceptScore W2083624877C2779066055 @default.
- W2083624877 hasConceptScore W2083624877C2780486903 @default.
- W2083624877 hasConceptScore W2083624877C2780912031 @default.
- W2083624877 hasConceptScore W2083624877C28212737 @default.
- W2083624877 hasConceptScore W2083624877C515207424 @default.
- W2083624877 hasConceptScore W2083624877C55493867 @default.
- W2083624877 hasConceptScore W2083624877C71924100 @default.
- W2083624877 hasConceptScore W2083624877C8264082 @default.
- W2083624877 hasConceptScore W2083624877C88189869 @default.
- W2083624877 hasIssue "3" @default.
- W2083624877 hasLocation W20836248771 @default.
- W2083624877 hasLocation W20836248772 @default.
- W2083624877 hasOpenAccess W2083624877 @default.
- W2083624877 hasPrimaryLocation W20836248771 @default.
- W2083624877 hasRelatedWork W1969419739 @default.
- W2083624877 hasRelatedWork W1997007826 @default.
- W2083624877 hasRelatedWork W2002384464 @default.
- W2083624877 hasRelatedWork W2059229723 @default.
- W2083624877 hasRelatedWork W2086583026 @default.
- W2083624877 hasRelatedWork W2108578925 @default.
- W2083624877 hasRelatedWork W2137013713 @default.
- W2083624877 hasRelatedWork W2149799471 @default.
- W2083624877 hasRelatedWork W2156499301 @default.
- W2083624877 hasRelatedWork W2167902350 @default.
- W2083624877 hasVolume "16" @default.
- W2083624877 isParatext "false" @default.
- W2083624877 isRetracted "false" @default.
- W2083624877 magId "2083624877" @default.
- W2083624877 workType "article" @default.