FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083669433> ?p ?o ?g. }

• W2083669433 endingPage "383" @default.
• W2083669433 startingPage "375" @default.
• W2083669433 abstract "The aims of this research were to develop a novel bilayer hydrocolloid film based on alginate and to investigate its potential as slow-release wound healing vehicle. The bilayer is composed of an upper layer impregnated with model drug (ibuprofen) and a drug-free lower layer, which acted as a rate-controlling membrane. The thickness uniformity, solvent loss, moisture vapour transmission rate (MVTR), hydration rate, morphology, rheology, mechanical properties, in vitro drug release and in vivo wound healing profiles were investigated. A smooth bilayer film with two homogenous distinct layers was produced. The characterisation results showed that bilayer has superior mechanical and rheological properties than the single layer films. The bilayers also showed low MVTR, slower hydration rate and lower drug flux in vitro compared to single layer inferring that bilayer may be useful for treating low suppurating wounds and suitable for slow release application on wound surfaces. The bilayers also provided a significant higher healing rate in vivo, with well-formed epidermis with faster granulation tissue formation when compared to the controls. In conclusions, a novel alginate-based bilayer hydrocolloid film was developed and results suggested that they can be exploited as slow-release wound dressings." @default.
• W2083669433 created "2016-06-24" @default.
• W2083669433 creator A5013596679 @default.
• W2083669433 creator A5031635745 @default.
• W2083669433 creator A5069074647 @default.
• W2083669433 date "2012-09-01" @default.
• W2083669433 modified "2023-10-18" @default.
• W2083669433 title "Alginate based bilayer hydrocolloid films as potential slow-release modern wound dressing" @default.
• W2083669433 cites W1975687689 @default.
• W2083669433 cites W1978139063 @default.
• W2083669433 cites W1986741782 @default.
• W2083669433 cites W1987312039 @default.
• W2083669433 cites W1988642238 @default.
• W2083669433 cites W2003758893 @default.
• W2083669433 cites W2007871965 @default.
• W2083669433 cites W2008978668 @default.
• W2083669433 cites W2009751641 @default.
• W2083669433 cites W2010996090 @default.
• W2083669433 cites W2011074794 @default.
• W2083669433 cites W2011992603 @default.
• W2083669433 cites W2016714257 @default.
• W2083669433 cites W2020338027 @default.
• W2083669433 cites W2020473652 @default.
• W2083669433 cites W2022183922 @default.
• W2083669433 cites W2031112424 @default.
• W2083669433 cites W2038085267 @default.
• W2083669433 cites W2039249444 @default.
• W2083669433 cites W2047497983 @default.
• W2083669433 cites W2053954791 @default.
• W2083669433 cites W2061722662 @default.
• W2083669433 cites W2062484389 @default.
• W2083669433 cites W2068274850 @default.
• W2083669433 cites W2071131056 @default.
• W2083669433 cites W2073298577 @default.
• W2083669433 cites W2074829751 @default.
• W2083669433 cites W2076950376 @default.
• W2083669433 cites W2085379114 @default.
• W2083669433 cites W2091080098 @default.
• W2083669433 cites W2094591231 @default.
• W2083669433 cites W2100368139 @default.
• W2083669433 cites W2120679327 @default.
• W2083669433 cites W2147038478 @default.
• W2083669433 cites W2151350356 @default.
• W2083669433 cites W2159915088 @default.
• W2083669433 cites W2163900528 @default.
• W2083669433 doi "https://doi.org/10.1016/j.ijpharm.2012.05.044" @default.
• W2083669433 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22643226" @default.
• W2083669433 hasPublicationYear "2012" @default.
• W2083669433 type Work @default.
• W2083669433 sameAs 2083669433 @default.
• W2083669433 citedByCount "205" @default.
• W2083669433 countsByYear W20836694332012 @default.
• W2083669433 countsByYear W20836694332013 @default.
• W2083669433 countsByYear W20836694332014 @default.
• W2083669433 countsByYear W20836694332015 @default.
• W2083669433 countsByYear W20836694332016 @default.
• W2083669433 countsByYear W20836694332017 @default.
• W2083669433 countsByYear W20836694332018 @default.
• W2083669433 countsByYear W20836694332019 @default.
• W2083669433 countsByYear W20836694332020 @default.
• W2083669433 countsByYear W20836694332021 @default.
• W2083669433 countsByYear W20836694332022 @default.
• W2083669433 countsByYear W20836694332023 @default.
• W2083669433 crossrefType "journal-article" @default.
• W2083669433 hasAuthorship W2083669433A5013596679 @default.
• W2083669433 hasAuthorship W2083669433A5031635745 @default.
• W2083669433 hasAuthorship W2083669433A5069074647 @default.
• W2083669433 hasConcept C12554922 @default.
• W2083669433 hasConcept C127413603 @default.
• W2083669433 hasConcept C141071460 @default.
• W2083669433 hasConcept C159985019 @default.
• W2083669433 hasConcept C171250308 @default.
• W2083669433 hasConcept C185592680 @default.
• W2083669433 hasConcept C192157962 @default.
• W2083669433 hasConcept C192562407 @default.
• W2083669433 hasConcept C2779227376 @default.
• W2083669433 hasConcept C2780269544 @default.
• W2083669433 hasConcept C41625074 @default.
• W2083669433 hasConcept C42360764 @default.
• W2083669433 hasConcept C55493867 @default.
• W2083669433 hasConcept C71924100 @default.
• W2083669433 hasConcept C86803240 @default.
• W2083669433 hasConcept C88463166 @default.
• W2083669433 hasConceptScore W2083669433C12554922 @default.
• W2083669433 hasConceptScore W2083669433C127413603 @default.
• W2083669433 hasConceptScore W2083669433C141071460 @default.
• W2083669433 hasConceptScore W2083669433C159985019 @default.
• W2083669433 hasConceptScore W2083669433C171250308 @default.
• W2083669433 hasConceptScore W2083669433C185592680 @default.
• W2083669433 hasConceptScore W2083669433C192157962 @default.
• W2083669433 hasConceptScore W2083669433C192562407 @default.
• W2083669433 hasConceptScore W2083669433C2779227376 @default.
• W2083669433 hasConceptScore W2083669433C2780269544 @default.
• W2083669433 hasConceptScore W2083669433C41625074 @default.
• W2083669433 hasConceptScore W2083669433C42360764 @default.
• W2083669433 hasConceptScore W2083669433C55493867 @default.
• W2083669433 hasConceptScore W2083669433C71924100 @default.
• W2083669433 hasConceptScore W2083669433C86803240 @default.

• next