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- W2083670359 abstract "Gingival exudate and serum were collected from 23 patients with extensive periodontitis. The depths of the periodontal pockets were measured on the upper canine and incisor teeth, while the amount of bone loss in the same regions was evaluated on radiographs. Assays of β-glucuronidase activity have shown very high levels of the enzyme in gingival fluid, as compared to the enzyme concentrations found in serum. A positive, statistically significant correlation was found between the concentrations of β-glucuronidase in gingival exudate and the depths of the periodontal pockets, as well as the amount of bone loss. A positive, statistically significant correlation was also noticed between the activities of the enzyme in gingival fluid and those of serum, but the serum enzyme values remained within normal limits. L'exsudat gingival et le serum de 23 patients, atteints de parodontite avancée sont prélevés. Les profondeurs des poches parodontales sont mesurées au niveau de la canine et de l'incisive supérieures, alors que la perte osseuse est appréciée à l'aide de radiographies. Des essais d'activités de la β-glucuronidase ont montré la présence de concentrations élevées de l'enzyme dans le fluide gingival, lorsqu'on la compare à celle du sérum. Un rapport positif, statistiquement significatif, est observé entre lesconcentrations en β-glucuronidase de l'exsudat gingival et la profondeur des poches parodontales et l'importance de la perte osseuse. Un rapport du même ordre est aussi noté entre les activités de l'enzyme dans le fluide gingival et celles du sérum, mais les valeurs de l'enzyme dans ce dernier restent dans des limites normales. Gingivales Exsudat und Serum wurden von 23 Patienten mit ausgedehnter Parodontitis gesammelt. Die Tiefen der parodontalen Taschen wurden am oberen Eckzahn und an den Schneidezähnen gemessen, während das Ausmaβ des Knochenverlustes im selben Bezirk röntgenologisch festgestellt wurde. Die Bestimmungen der β-Glucoronidase-Aktivität ergaben sehr hohe Enzym-Spiegel in der Gingivaflüssigkeit im Vergleich zu den Enzym-Konzentrationen im Serum. Eine positive, statistisch signifikante Korrelation bestand zwischen den Konzentrationen der β-Glucoronidase im gingivalen Exsudat und der Tiefe der parodontalen Taschen wie auch zum Ausmaβ des Knochenverlustes. Weiterhin wurde eine positive, statistisch signifikante Korrelation zwischen den Enzym-Aktivitäten in der Gingivaflüssigkeit und im Serum beobachtet, wobei jedoch die Serum-Enzymwerte innerhalb normaler Grenzen blieben." @default.
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- W2083670359 title "Beta-glucuronidase correlated with inflammation in the exudate from human gingiva" @default.
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- W2083670359 doi "https://doi.org/10.1016/0003-9969(70)90071-3" @default.
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