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• W2083710085 abstract "The purpose of this study was to assess the use of a multivariate statistical method to rank clinical and gait variables, thus describing a ranking of patient dysfunction prior to and following total knee replacement (TKR) surgery. Twenty end-stage knee osteoarthritis (KOA) subjects scheduled for TKR and 20 healthy controls performed level walking and stair ascent twice: pre- (P1) and 6 months post-surgery (P2). Clinical and gait measures were entered into a principle component analysis (PCA) to determine orthogonal principle components (PCs). The PCs were entered into a discriminant function analysis to determine the best predictors of group membership. The PCA extracted three PCs for both the P1 and P2 data sets. Three orthogonal dimensions were formed: knee dysfunction, gait dysfunction, and stair ascent dysfunction. For P1 the knee dysfunction dimension composed of both subjective and objective measures, best discriminated between end-stage knee osteoarthritis patients and controls. For P2, the stair ascent dysfunction dimension best discriminated between 6 months post-TKR patients and controls. The results of this study suggest that a multivariate statistical method provides a clinically relevant ranking of patient dysfunction prior to and following TKR. This ranking of dysfunction could serve to identify rehabilitation priorities." @default.
• W2083710085 created "2016-06-24" @default.
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• W2083710085 date "2009-08-01" @default.
• W2083710085 modified "2023-10-16" @default.
• W2083710085 title "A multivariate statistical ranking of clinical and gait measures before and after total knee replacement" @default.
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• W2083710085 doi "https://doi.org/10.1016/j.gaitpost.2009.04.009" @default.
• W2083710085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19464893" @default.
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