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- W2083713273 abstract "Abstract The toxicity of asiaticoside to skin in vitro was investigated by a microrespiration technique and by histology. Compared with other therapeutic agents the toxicity of asiaticoside was not excessive. The effect of asiaticoside on the biosynthesis of skin mucopolysaccharides and collagen was also investigated in vitro . Toxic effects to both processes were evaluated; these were comparable to the effect of asiaticoside on skin respiration. Histology showed that certain concentrations of asiaticoside affected the epidermis, possibly increasing keratinisation. There was no evidence that asiaticoside stimulated either respiration or biosynthesis of ground substance. Asiaticoside failed to influence the mortality and healing of experimental burns in mice." @default.
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- W2083713273 date "1967-09-01" @default.
- W2083713273 modified "2023-10-17" @default.
- W2083713273 title "The morphological and pharmacological effects of asiaticoside upon skin in vitro and in vivo" @default.
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- W2083713273 doi "https://doi.org/10.1016/0014-2999(67)90104-5" @default.
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