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• W2083786338 abstract "In the myenteric plexus-longitudinal muscle bioassay, beta-endorphin, i.e., beta-lipotropin (beta-LPH)-[61-91], has a potency of 450 with confidence limits of 281-966 when Met5-enkephalin is used as a reference standard with a potency of 100. The primary amide and the ethylamide of Met5-enkephalin have potencies statistically overlapping with that of beta-endorphin. The primary amide of alpha-endorphin has twice the potency of the free acid form of alpha-endorphin. An intact NH2-terminal tyrosine is not necessary for full intrinsic activity. The shortest fragment of beta-LPH with morphinomimetic activity is beta-LPH-[61-64]." @default.
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• W2083786338 date "1976-09-01" @default.
• W2083786338 modified "2023-09-25" @default.
• W2083786338 title "Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs." @default.
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• W2083786338 doi "https://doi.org/10.1073/pnas.73.9.3308" @default.
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