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- W2083803990 abstract "Abstract The adsorption of fibrinogen, a plasma protein, and heparin, an anticoagulant on insulator materials, glass and polymethyl methacrylate was investigated. The technique of streaming potential determination was employed. The protein and the drug were dissolved in a dilute Krebs solution (containing CaCl 2 , NaCl, NaHCO 3 , KH 2 PO 4 , MgSO 4 and KCl) and the streaming potentials developed when the solutions were flowed at pressures up to 40 cm of mercury were recorded. The results show that even at a very low concentration (10 μg ml −1 ) fibrinogen reduced significantly the zeta potential of glass and polymethyl methacrylate. Subsequent addition of heparin to the solution had little effect on glass but slightly enhanced the zeta potential of the acrylic polymer. The effect due to fibrinogen persists even after pre-treatment of the surface with heparin." @default.
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- W2083803990 title "Adsorption of fibrinogen and heparin on insulator surfaces — an electrokinetic study" @default.
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