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- W2083808049 abstract "Titanium is the material of choice for oral implantology. The superiority of titanium comes from its mechanical, physicochemical, and biological properties, particularly immunotolerance and cytocompatibility1,2). However because of needs to improve its mechanical properties, titanium alloys such as Ti-6Al-4V, Ti-6Al-7Nb, have also been used for dental and orthopedic material3-5).1) Although titanium alloys are still widely used in medicine, some concern has been expressed over its use since it appears that small amounts of both vanadium and aluminum, released in the human body, induce possible cytotoxic effect and neurological disorders, respectively6-8). In terms of mechanical properties, Ti-6Al-4V alloy belongs to α+β type titanium alloy family. The rigidity of α+β type titanium alloy is much higher (about 120 GPa) than that of the cortical bone (Max 30 GPa)9). Such a strong rigidity (a large modulus of elasticity) causes insufficient loading of the bone adjacent to the implant. This is often referred to as the stress-shielding phenomenon and can lead to potential bone resorption and eventual failure of the implant10). Consequently the recent trend in research and development of titanium alloys for biomedical application is to develop low rigidity titanium alloys composed of non-toxic and non-allergenic elements with excellent mechanical properties and workability9,10). The most promising materials are the β-type titanium alloys because their elastic moduli are smaller than that of αor α+β type titanium family. Therefore new β-type titanium alloys which are composed of non-toxic elements like Tantalum (Ta), Niobium (Nb), Zirconium (Zr)," @default.
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- W2083808049 date "2006-01-01" @default.
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- W2083808049 title "Biocompatibility of Ti-8Ta-3Nb alloy with fetal rat calvarial cells" @default.
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- W2083808049 doi "https://doi.org/10.5051/jkape.2006.36.4.849" @default.
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