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- W2083862783 abstract "To the Editor: Gefitinib is an orally active inhibitor of tyrosine kinase epidermal growth factor,1 with clinical effectiveness in the control of non–small-cell lung cancer. We describe 3 patients with possible treatment-related acute promyelocytic leukemia (APL) among 108 consecutive patients with advanced, recurrent non–small-cell lung cancer who were treated with gefitinib between November 2001 and December 2004 at our institution (Table 1). Other than these three patients, no patients with other cancers have been identified in this cohort. Chemotherapy, including the use of topoisomerase II inhibitors (e.g., anthracyclines), and radiotherapy are known as predisposing factors for treatment-related APL,2 and all . . ." @default.
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- W2083862783 date "2005-02-24" @default.
- W2083862783 modified "2023-09-24" @default.
- W2083862783 title "APL during Gefitinib Treatment for Non–Small-Cell Lung Cancer" @default.
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- W2083862783 doi "https://doi.org/10.1056/nejm200502243520825" @default.
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