Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083882897> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2083882897 abstract "Ovarian cancers metastasize by shedding into the peritoneal fluid and dispersing to distal sites within the peritoneum. Monolayer cultures do not accurately model the behaviors of cancer cells within a nonadherent environment, as cancer cells inherently aggregate into multicellular structures which contribute to the metastatic process by attaching to and invading the peritoneal lining to form secondary tumors. To model this important stage of ovarian cancer metastasis, multicellular aggregates, or spheroids, can be generated from established ovarian cancer cell lines maintained under nonadherent conditions. To mimic the peritoneal microenvironment encountered by tumor cells in vivo, a spheroid-mesothelial co-culture model was established in which preformed spheroids are plated on top of a human mesothelial cell monolayer, formed over an extracellular matrix barrier. Methods were then developed using a real-time cell analyzer to conduct quantitative real time measurements of the invasive capacity of different ovarian cancer cell lines grown as spheroids. This approach allows for the continuous measurement of invasion over long periods of time, which has several advantages over traditional endpoint assays and more laborious real time microscopy image analyses. In short, this method enables a rapid, determination of factors which regulate the interactions between ovarian cancer spheroid cells invading through mesothelial and matrix barriers over time." @default.
- W2083882897 created "2016-06-24" @default.
- W2083882897 creator A5034848117 @default.
- W2083882897 creator A5045883594 @default.
- W2083882897 date "2014-05-20" @default.
- W2083882897 modified "2023-09-24" @default.
- W2083882897 title "Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time" @default.
- W2083882897 cites W1920390126 @default.
- W2083882897 cites W1968002492 @default.
- W2083882897 cites W1981989535 @default.
- W2083882897 cites W1996081149 @default.
- W2083882897 cites W1996604878 @default.
- W2083882897 cites W1997559135 @default.
- W2083882897 cites W2005071828 @default.
- W2083882897 cites W2006108842 @default.
- W2083882897 cites W2009211019 @default.
- W2083882897 cites W2031721844 @default.
- W2083882897 cites W2042633087 @default.
- W2083882897 cites W2047311008 @default.
- W2083882897 cites W2056569074 @default.
- W2083882897 cites W2089462778 @default.
- W2083882897 cites W2100926855 @default.
- W2083882897 cites W2106876536 @default.
- W2083882897 cites W2121452569 @default.
- W2083882897 cites W2137750805 @default.
- W2083882897 cites W2410943859 @default.
- W2083882897 doi "https://doi.org/10.3791/51655" @default.
- W2083882897 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4199467" @default.
- W2083882897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24893837" @default.
- W2083882897 hasPublicationYear "2014" @default.
- W2083882897 type Work @default.
- W2083882897 sameAs 2083882897 @default.
- W2083882897 citedByCount "16" @default.
- W2083882897 countsByYear W20838828972015 @default.
- W2083882897 countsByYear W20838828972016 @default.
- W2083882897 countsByYear W20838828972017 @default.
- W2083882897 countsByYear W20838828972018 @default.
- W2083882897 countsByYear W20838828972019 @default.
- W2083882897 countsByYear W20838828972020 @default.
- W2083882897 countsByYear W20838828972021 @default.
- W2083882897 countsByYear W20838828972023 @default.
- W2083882897 crossrefType "journal-article" @default.
- W2083882897 hasAuthorship W2083882897A5034848117 @default.
- W2083882897 hasAuthorship W2083882897A5045883594 @default.
- W2083882897 hasBestOaLocation W20838828971 @default.
- W2083882897 hasConcept C121608353 @default.
- W2083882897 hasConcept C142724271 @default.
- W2083882897 hasConcept C1491633281 @default.
- W2083882897 hasConcept C175369904 @default.
- W2083882897 hasConcept C185592680 @default.
- W2083882897 hasConcept C189165786 @default.
- W2083882897 hasConcept C2779013556 @default.
- W2083882897 hasConcept C2779747549 @default.
- W2083882897 hasConcept C2780427987 @default.
- W2083882897 hasConcept C2909640154 @default.
- W2083882897 hasConcept C502942594 @default.
- W2083882897 hasConcept C54355233 @default.
- W2083882897 hasConcept C71924100 @default.
- W2083882897 hasConcept C81885089 @default.
- W2083882897 hasConcept C86803240 @default.
- W2083882897 hasConcept C95444343 @default.
- W2083882897 hasConcept C96232424 @default.
- W2083882897 hasConceptScore W2083882897C121608353 @default.
- W2083882897 hasConceptScore W2083882897C142724271 @default.
- W2083882897 hasConceptScore W2083882897C1491633281 @default.
- W2083882897 hasConceptScore W2083882897C175369904 @default.
- W2083882897 hasConceptScore W2083882897C185592680 @default.
- W2083882897 hasConceptScore W2083882897C189165786 @default.
- W2083882897 hasConceptScore W2083882897C2779013556 @default.
- W2083882897 hasConceptScore W2083882897C2779747549 @default.
- W2083882897 hasConceptScore W2083882897C2780427987 @default.
- W2083882897 hasConceptScore W2083882897C2909640154 @default.
- W2083882897 hasConceptScore W2083882897C502942594 @default.
- W2083882897 hasConceptScore W2083882897C54355233 @default.
- W2083882897 hasConceptScore W2083882897C71924100 @default.
- W2083882897 hasConceptScore W2083882897C81885089 @default.
- W2083882897 hasConceptScore W2083882897C86803240 @default.
- W2083882897 hasConceptScore W2083882897C95444343 @default.
- W2083882897 hasConceptScore W2083882897C96232424 @default.
- W2083882897 hasIssue "87" @default.
- W2083882897 hasLocation W20838828971 @default.
- W2083882897 hasLocation W20838828972 @default.
- W2083882897 hasLocation W20838828973 @default.
- W2083882897 hasLocation W20838828974 @default.
- W2083882897 hasOpenAccess W2083882897 @default.
- W2083882897 hasPrimaryLocation W20838828971 @default.
- W2083882897 hasRelatedWork W2083882897 @default.
- W2083882897 hasRelatedWork W2092007485 @default.
- W2083882897 hasRelatedWork W2591274026 @default.
- W2083882897 hasRelatedWork W2885012433 @default.
- W2083882897 hasRelatedWork W2898478773 @default.
- W2083882897 hasRelatedWork W4206970703 @default.
- W2083882897 hasRelatedWork W4286855312 @default.
- W2083882897 hasRelatedWork W4304116770 @default.
- W2083882897 hasRelatedWork W4324262950 @default.
- W2083882897 hasRelatedWork W4380051839 @default.
- W2083882897 isParatext "false" @default.
- W2083882897 isRetracted "false" @default.
- W2083882897 magId "2083882897" @default.
- W2083882897 workType "article" @default.