Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083910391> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2083910391 endingPage "335" @default.
- W2083910391 startingPage "333" @default.
- W2083910391 abstract "In this proof-of principle study, we determined whether biocompatible, biodegradable and sterically stabilized phospholipid nanomicelles (SSNMs) improve viability and membrane integrity of cryopreserved oral keratinocytes. Cultured chemically transformed hamster oral keratinocytes were frozen gradually with and stored in liquid nitrogen in the presence of 10% dimethylsulfoxide (DMSO) or SSNMs composed of distearoylphosphatidyl-ethanolamine-N-poly(ethylene glycol) 2000 (size, 17+/-1nm; 0.1 and 1.0nmol). Forty-eight hours later, cells were thawed and their viability was determined. Lactate dehydrogenase (LDH) activity in cell lysates and supernatants was quantified as well. SSNMs evoked a significant, concentration-dependant increase in cell viability in comparison to 10% DMSO (p<0.05). There was also a significant decrease in LDH activity in the supernatant of cells cryopreserved with SSNMs in comparison to 10% DMSO (p<0.05). These data indicate that SSNMs improve cryopreservation of oral keratinocyte by promoting cell viability and plasma membrane integrity. We suggest that SSNMs should be further developed as a novel nanocryopreservative for keratinocytes." @default.
- W2083910391 created "2016-06-24" @default.
- W2083910391 creator A5004947609 @default.
- W2083910391 creator A5028700223 @default.
- W2083910391 date "2007-06-01" @default.
- W2083910391 modified "2023-09-27" @default.
- W2083910391 title "Biocompatible, biodegradable and sterically stabilized phospholipid nanomicelles improve cryopreservation of oral keratinocytes: A preliminary investigation" @default.
- W2083910391 cites W1266373835 @default.
- W2083910391 cites W1959429077 @default.
- W2083910391 cites W2000074487 @default.
- W2083910391 cites W2000808207 @default.
- W2083910391 cites W2011436507 @default.
- W2083910391 cites W2034499124 @default.
- W2083910391 cites W2058109507 @default.
- W2083910391 cites W2088800606 @default.
- W2083910391 cites W2125832587 @default.
- W2083910391 cites W2127324368 @default.
- W2083910391 cites W233471670 @default.
- W2083910391 doi "https://doi.org/10.1016/j.ijpharm.2007.02.002" @default.
- W2083910391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17344000" @default.
- W2083910391 hasPublicationYear "2007" @default.
- W2083910391 type Work @default.
- W2083910391 sameAs 2083910391 @default.
- W2083910391 citedByCount "4" @default.
- W2083910391 countsByYear W20839103912012 @default.
- W2083910391 countsByYear W20839103912014 @default.
- W2083910391 countsByYear W20839103912017 @default.
- W2083910391 crossrefType "journal-article" @default.
- W2083910391 hasAuthorship W2083910391A5004947609 @default.
- W2083910391 hasAuthorship W2083910391A5028700223 @default.
- W2083910391 hasConcept C1491633281 @default.
- W2083910391 hasConcept C178790620 @default.
- W2083910391 hasConcept C179933525 @default.
- W2083910391 hasConcept C181199279 @default.
- W2083910391 hasConcept C185592680 @default.
- W2083910391 hasConcept C196843134 @default.
- W2083910391 hasConcept C202751555 @default.
- W2083910391 hasConcept C2777074287 @default.
- W2083910391 hasConcept C2777318727 @default.
- W2083910391 hasConcept C2777516009 @default.
- W2083910391 hasConcept C2778918659 @default.
- W2083910391 hasConcept C41625074 @default.
- W2083910391 hasConcept C53227056 @default.
- W2083910391 hasConcept C55493867 @default.
- W2083910391 hasConcept C86803240 @default.
- W2083910391 hasConcept C95444343 @default.
- W2083910391 hasConceptScore W2083910391C1491633281 @default.
- W2083910391 hasConceptScore W2083910391C178790620 @default.
- W2083910391 hasConceptScore W2083910391C179933525 @default.
- W2083910391 hasConceptScore W2083910391C181199279 @default.
- W2083910391 hasConceptScore W2083910391C185592680 @default.
- W2083910391 hasConceptScore W2083910391C196843134 @default.
- W2083910391 hasConceptScore W2083910391C202751555 @default.
- W2083910391 hasConceptScore W2083910391C2777074287 @default.
- W2083910391 hasConceptScore W2083910391C2777318727 @default.
- W2083910391 hasConceptScore W2083910391C2777516009 @default.
- W2083910391 hasConceptScore W2083910391C2778918659 @default.
- W2083910391 hasConceptScore W2083910391C41625074 @default.
- W2083910391 hasConceptScore W2083910391C53227056 @default.
- W2083910391 hasConceptScore W2083910391C55493867 @default.
- W2083910391 hasConceptScore W2083910391C86803240 @default.
- W2083910391 hasConceptScore W2083910391C95444343 @default.
- W2083910391 hasIssue "1-2" @default.
- W2083910391 hasLocation W20839103911 @default.
- W2083910391 hasLocation W20839103912 @default.
- W2083910391 hasOpenAccess W2083910391 @default.
- W2083910391 hasPrimaryLocation W20839103911 @default.
- W2083910391 hasRelatedWork W1969001620 @default.
- W2083910391 hasRelatedWork W1969931942 @default.
- W2083910391 hasRelatedWork W2010196354 @default.
- W2083910391 hasRelatedWork W2060397639 @default.
- W2083910391 hasRelatedWork W2062573760 @default.
- W2083910391 hasRelatedWork W2069540150 @default.
- W2083910391 hasRelatedWork W2083910391 @default.
- W2083910391 hasRelatedWork W2353219288 @default.
- W2083910391 hasRelatedWork W2396032916 @default.
- W2083910391 hasRelatedWork W3080586264 @default.
- W2083910391 hasVolume "338" @default.
- W2083910391 isParatext "false" @default.
- W2083910391 isRetracted "false" @default.
- W2083910391 magId "2083910391" @default.
- W2083910391 workType "article" @default.