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- W2083968198 abstract "Five hundred thirty-one patients with chronic bifascicular block and intact atrioventricular (A-V) conduction were studied and prospectively followed up to ascertain the effect of age on both severity of conduction defect and life history. The patients were subdivided into a younger group, aged 18 to 59 years, and an older group, aged 60 and above. They were further separated into those with primary conduction disease (118 patients) and those with organic heart disease (413 patients). In the patients with primary conduction disease, the findings were as follows (younger group, 60 patients, versus older group, 58 patients) (mean ± standard error of the mean): age 43 ± 1.4 versus 73 ± 1.1 (p < 0.001); A-H Interval 92 ± 3.8 versus 100 ± 3.8 ms (not significant); H-V interval 48 ± 1.6 versus 49 ± 1.6 ms (not significant). Progression to spontaneous A-V block was noted in no younger patient and one older patient (not significant) over a mean follow-up period of 3.5 ± 0.3 years. The 5 year total cumulative mortality was significantly higher in the older group with no difference in the incidence of sudden death in the two groups. In patients with organic heart disease, the findings were as follows (younger group, 170 patients, versus older group, 243 patients): age 48 ± 0.9 versus 71 ± 0.5 (p < 0.001); A-H interval 105 ± 2.3 versus 114 ±3.1 ms (p < 0.05); H-V interval 54 ± 1.3 versus 55 ± 0.9 ms (not significant). Progression to spontaneous A-V block was seen in six patients (3 percent) in the younger group and 15 (5 percent) in the older group (not significant). The 5 year total cumulative mortality was significantly higher in the older group with no difference in the incidence of sudden death in the two groups. With the exception of the A-H interval in the group with organic heart disease, the severity and progression of conduction disease were independent of advanced age in patients with chronic bifascicular block." @default.
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- W2083968198 date "1980-04-01" @default.
- W2083968198 modified "2023-10-16" @default.
- W2083968198 title "Effect of age on atrioventricular conduction in patients with chronic bifascicular block" @default.
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- W2083968198 doi "https://doi.org/10.1016/0002-9149(80)90117-4" @default.
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