Matches in SemOpenAlex for { <https://semopenalex.org/work/W2083978840> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2083978840 endingPage "248" @default.
- W2083978840 startingPage "239" @default.
- W2083978840 abstract "Previous types of rock wool has been recently replaced with high-temperature wool (HT wool). HT wool is characterized by a chemical composition with a higher concentration of Al(2)O(3) and a lower concentration of SiO(2), lower biopersistence, and a higher melting point than previous types of rock wool. To evaluate the safety of HT wool, an asbestos substitute, we examined the biopersistence of HT wool in the lungs, based on changes in fiber count according to the length and fiber size (length and width), by performing a nose-only inhalation exposure study in rats.Male Fischer 344 rats were exposed to fibers at the target exposure concentration of 30 mg/m(3) continuously for 3 hours daily for 5 consecutive days. Rats were sacrificed shortly after exposure, and 1, 2, and 4 weeks after exposure, and their lung tissues were incinerated at a low temperature. Then, fiber counts and sizes in the lungs were analyzed using a phase contrast microscope.The fiber count in the lungs 4 weeks after exposure significantly decreased from the baseline value (shortly after exposure). The half-life of fibers calculated from the approximation curve was 34 days for all fibers and 11 days for fibers longer than 20 μm.Both the length and width significantly decreased 4 weeks after exposure, probably because fibers were ingested by alveolar macrophages, discharged to outside of the body by mucociliary movement, or lysed by body fluid. In future studies, it is necessary to examine the long-term persistence of fibers in the lungs." @default.
- W2083978840 created "2016-06-24" @default.
- W2083978840 creator A5001334483 @default.
- W2083978840 creator A5011346406 @default.
- W2083978840 creator A5011625983 @default.
- W2083978840 creator A5020062264 @default.
- W2083978840 creator A5033307186 @default.
- W2083978840 creator A5036273875 @default.
- W2083978840 creator A5048491988 @default.
- W2083978840 creator A5055227838 @default.
- W2083978840 date "2005-09-01" @default.
- W2083978840 modified "2023-10-18" @default.
- W2083978840 title "Behavior of new type of rock wool (HT wool) in lungs after exposure by nasal inhalation in rats" @default.
- W2083978840 cites W1972641496 @default.
- W2083978840 cites W2024504440 @default.
- W2083978840 cites W2039708618 @default.
- W2083978840 cites W2040206934 @default.
- W2083978840 cites W2066058093 @default.
- W2083978840 cites W2097900817 @default.
- W2083978840 cites W2111974647 @default.
- W2083978840 cites W2128618977 @default.
- W2083978840 cites W2164563868 @default.
- W2083978840 doi "https://doi.org/10.1007/bf02897697" @default.
- W2083978840 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2723406" @default.
- W2083978840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21432126" @default.
- W2083978840 hasPublicationYear "2005" @default.
- W2083978840 type Work @default.
- W2083978840 sameAs 2083978840 @default.
- W2083978840 citedByCount "10" @default.
- W2083978840 countsByYear W20839788402018 @default.
- W2083978840 countsByYear W20839788402021 @default.
- W2083978840 countsByYear W20839788402022 @default.
- W2083978840 countsByYear W20839788402023 @default.
- W2083978840 crossrefType "journal-article" @default.
- W2083978840 hasAuthorship W2083978840A5001334483 @default.
- W2083978840 hasAuthorship W2083978840A5011346406 @default.
- W2083978840 hasAuthorship W2083978840A5011625983 @default.
- W2083978840 hasAuthorship W2083978840A5020062264 @default.
- W2083978840 hasAuthorship W2083978840A5033307186 @default.
- W2083978840 hasAuthorship W2083978840A5036273875 @default.
- W2083978840 hasAuthorship W2083978840A5048491988 @default.
- W2083978840 hasAuthorship W2083978840A5055227838 @default.
- W2083978840 hasBestOaLocation W20839788402 @default.
- W2083978840 hasConcept C105702510 @default.
- W2083978840 hasConcept C126322002 @default.
- W2083978840 hasConcept C140793950 @default.
- W2083978840 hasConcept C159985019 @default.
- W2083978840 hasConcept C178790620 @default.
- W2083978840 hasConcept C185592680 @default.
- W2083978840 hasConcept C192562407 @default.
- W2083978840 hasConcept C2775951321 @default.
- W2083978840 hasConcept C2776954882 @default.
- W2083978840 hasConcept C2777714996 @default.
- W2083978840 hasConcept C2779777708 @default.
- W2083978840 hasConcept C519885992 @default.
- W2083978840 hasConcept C71924100 @default.
- W2083978840 hasConcept C86803240 @default.
- W2083978840 hasConceptScore W2083978840C105702510 @default.
- W2083978840 hasConceptScore W2083978840C126322002 @default.
- W2083978840 hasConceptScore W2083978840C140793950 @default.
- W2083978840 hasConceptScore W2083978840C159985019 @default.
- W2083978840 hasConceptScore W2083978840C178790620 @default.
- W2083978840 hasConceptScore W2083978840C185592680 @default.
- W2083978840 hasConceptScore W2083978840C192562407 @default.
- W2083978840 hasConceptScore W2083978840C2775951321 @default.
- W2083978840 hasConceptScore W2083978840C2776954882 @default.
- W2083978840 hasConceptScore W2083978840C2777714996 @default.
- W2083978840 hasConceptScore W2083978840C2779777708 @default.
- W2083978840 hasConceptScore W2083978840C519885992 @default.
- W2083978840 hasConceptScore W2083978840C71924100 @default.
- W2083978840 hasConceptScore W2083978840C86803240 @default.
- W2083978840 hasIssue "5" @default.
- W2083978840 hasLocation W20839788401 @default.
- W2083978840 hasLocation W20839788402 @default.
- W2083978840 hasLocation W20839788403 @default.
- W2083978840 hasLocation W20839788404 @default.
- W2083978840 hasOpenAccess W2083978840 @default.
- W2083978840 hasPrimaryLocation W20839788401 @default.
- W2083978840 hasRelatedWork W1984587338 @default.
- W2083978840 hasRelatedWork W2003685547 @default.
- W2083978840 hasRelatedWork W2008152807 @default.
- W2083978840 hasRelatedWork W2024295543 @default.
- W2083978840 hasRelatedWork W2029283892 @default.
- W2083978840 hasRelatedWork W2035302684 @default.
- W2083978840 hasRelatedWork W2041734698 @default.
- W2083978840 hasRelatedWork W4231263229 @default.
- W2083978840 hasRelatedWork W4234730524 @default.
- W2083978840 hasRelatedWork W4251061586 @default.
- W2083978840 hasVolume "10" @default.
- W2083978840 isParatext "false" @default.
- W2083978840 isRetracted "false" @default.
- W2083978840 magId "2083978840" @default.
- W2083978840 workType "article" @default.