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- W2083993313 abstract "Time-dependent ventilatory responses to episodic and continuous isocapnic hypoxia were measured in unidirectionally ventilated, awake ducks. Three protocols were used: (1) ten 3-min episodes of moderate hypoxia (10% O2) with 5-min normoxic intervals; (2) three 3-min episodes of severe hypoxia (8% O2) with 5-min normoxic intervals; and (3) 30-min of continuous moderate hypoxia. Ventilation (V̇i) increased immediately within a hypoxic episode (acute response), followed by a further slow rise in V̇i (short-term potentiation). The peak Vt response increased from the first to second moderate hypoxic episode (progressive augmentation), but was unchanged thereafter. During normoxic intervals, V̇i increased progressively (56% following the tenth episode; long term facilitation). Time-dependent changes were not observed during or following 30-min of continuous hypoxia. Although several time-dependent ventilatory responses to episodic hypoxia are observed in awake ducks, they are relatively small and biased towards facilitation versus inhibitory mechanisms." @default.
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- W2083993313 date "2001-01-01" @default.
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- W2083993313 title "Time domains of the hypoxic ventilatory response in awake ducks: episodic and continuous hypoxia" @default.
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- W2083993313 doi "https://doi.org/10.1016/s0034-5687(00)00197-3" @default.
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