FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084072271> ?p ?o ?g. }

• W2084072271 endingPage "25" @default.
• W2084072271 startingPage "16" @default.
• W2084072271 abstract "To evaluate the efficacy and safety of ganciclovir therapy in neonates with congenital cytomegalovirus (CMV) disease.Neonates with symptomatic CMV disease involving the central nervous system were randomly assigned to receive 6 weeks of intravenous ganciclovir versus no treatment. The primary end point was improved brainstem-evoked response (BSER) between baseline and 6-month follow-up (or, for patients with normal baseline hearing, normal BSER at both time points).From 1991 to 1999, 100 patients were enrolled. Of these, 42 patients had both a baseline and 6-month follow-up BSER audiometric examination and thus were evaluable for the primary end point. Twenty-one (84%) of 25 ganciclovir recipients had improved hearing or maintained normal hearing between baseline and 6 months versus 10 (59%) of 17 control patients (P=.06). None (0%) of 25 ganciclovir recipients had worsening in hearing between baseline and 6 months versus 7 (41%) of 17 control patients (P<.01). A total of 43 patients had a BSER at both baseline and at 1 year or beyond. Five (21%) of 24 ganciclovir recipients had worsening of hearing between baseline and > or =1 year versus 13 (68%) of 19 control patients (P<.01). A total of 89 patients had absolute neutrophil counts determined during the course of the study; 29 (63%) of 46 ganciclovir-treated patients had grade 3 or 4 neutropenia during treatment versus 9 (21%) of 43 control patients (P<.01).Ganciclovir therapy begun in the neonatal period in symptomatically infected infants with CMV infection involving the central nervous system prevents hearing deterioration at 6 months and may prevent hearing deterioration at > or =1 year. Almost two thirds of treated infants have significant neutropenia during therapy." @default.
• W2084072271 created "2016-06-24" @default.
• W2084072271 creator A5010573210 @default.
• W2084072271 creator A5017513685 @default.
• W2084072271 creator A5022971416 @default.
• W2084072271 creator A5023168748 @default.
• W2084072271 creator A5037870463 @default.
• W2084072271 creator A5041601658 @default.
• W2084072271 creator A5063561569 @default.
• W2084072271 creator A5063974025 @default.
• W2084072271 creator A5067038600 @default.
• W2084072271 creator A5078874999 @default.
• W2084072271 creator A5089821583 @default.
• W2084072271 creator A5090662177 @default.
• W2084072271 date "2003-07-01" @default.
• W2084072271 modified "2023-10-11" @default.
• W2084072271 title "Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial" @default.
• W2084072271 cites W1552823767 @default.
• W2084072271 cites W162801203 @default.
• W2084072271 cites W1647519295 @default.
• W2084072271 cites W1967271601 @default.
• W2084072271 cites W1986822882 @default.
• W2084072271 cites W1994778161 @default.
• W2084072271 cites W2002697635 @default.
• W2084072271 cites W2020469756 @default.
• W2084072271 cites W2031902234 @default.
• W2084072271 cites W2032092033 @default.
• W2084072271 cites W2034436943 @default.
• W2084072271 cites W2043195244 @default.
• W2084072271 cites W2045043963 @default.
• W2084072271 cites W2051699898 @default.
• W2084072271 cites W2064288175 @default.
• W2084072271 cites W2064601203 @default.
• W2084072271 cites W2067903431 @default.
• W2084072271 cites W2068162030 @default.
• W2084072271 cites W2079427812 @default.
• W2084072271 cites W2083598005 @default.
• W2084072271 cites W2094094522 @default.
• W2084072271 cites W2142682198 @default.
• W2084072271 cites W2149860264 @default.
• W2084072271 cites W4301900411 @default.
• W2084072271 cites W4366064475 @default.
• W2084072271 doi "https://doi.org/10.1016/s0022-3476(03)00192-6" @default.
• W2084072271 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12915819" @default.
• W2084072271 hasPublicationYear "2003" @default.
• W2084072271 type Work @default.
• W2084072271 sameAs 2084072271 @default.
• W2084072271 citedByCount "756" @default.
• W2084072271 countsByYear W20840722712012 @default.
• W2084072271 countsByYear W20840722712013 @default.
• W2084072271 countsByYear W20840722712014 @default.
• W2084072271 countsByYear W20840722712015 @default.
• W2084072271 countsByYear W20840722712016 @default.
• W2084072271 countsByYear W20840722712017 @default.
• W2084072271 countsByYear W20840722712018 @default.
• W2084072271 countsByYear W20840722712019 @default.
• W2084072271 countsByYear W20840722712020 @default.
• W2084072271 countsByYear W20840722712021 @default.
• W2084072271 countsByYear W20840722712022 @default.
• W2084072271 countsByYear W20840722712023 @default.
• W2084072271 crossrefType "journal-article" @default.
• W2084072271 hasAuthorship W2084072271A5010573210 @default.
• W2084072271 hasAuthorship W2084072271A5017513685 @default.
• W2084072271 hasAuthorship W2084072271A5022971416 @default.
• W2084072271 hasAuthorship W2084072271A5023168748 @default.
• W2084072271 hasAuthorship W2084072271A5037870463 @default.
• W2084072271 hasAuthorship W2084072271A5041601658 @default.
• W2084072271 hasAuthorship W2084072271A5063561569 @default.
• W2084072271 hasAuthorship W2084072271A5063974025 @default.
• W2084072271 hasAuthorship W2084072271A5067038600 @default.
• W2084072271 hasAuthorship W2084072271A5078874999 @default.
• W2084072271 hasAuthorship W2084072271A5089821583 @default.
• W2084072271 hasAuthorship W2084072271A5090662177 @default.
• W2084072271 hasConcept C126322002 @default.
• W2084072271 hasConcept C141071460 @default.
• W2084072271 hasConcept C168563851 @default.
• W2084072271 hasConcept C187212893 @default.
• W2084072271 hasConcept C203014093 @default.
• W2084072271 hasConcept C203092338 @default.
• W2084072271 hasConcept C2522874641 @default.
• W2084072271 hasConcept C2776409557 @default.
• W2084072271 hasConcept C2776694085 @default.
• W2084072271 hasConcept C2777063308 @default.
• W2084072271 hasConcept C2777732132 @default.
• W2084072271 hasConcept C2777965375 @default.
• W2084072271 hasConcept C2779820661 @default.
• W2084072271 hasConcept C2780727368 @default.
• W2084072271 hasConcept C71924100 @default.
• W2084072271 hasConceptScore W2084072271C126322002 @default.
• W2084072271 hasConceptScore W2084072271C141071460 @default.
• W2084072271 hasConceptScore W2084072271C168563851 @default.
• W2084072271 hasConceptScore W2084072271C187212893 @default.
• W2084072271 hasConceptScore W2084072271C203014093 @default.
• W2084072271 hasConceptScore W2084072271C203092338 @default.
• W2084072271 hasConceptScore W2084072271C2522874641 @default.
• W2084072271 hasConceptScore W2084072271C2776409557 @default.
• W2084072271 hasConceptScore W2084072271C2776694085 @default.
• W2084072271 hasConceptScore W2084072271C2777063308 @default.

• next