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- W2084077105 abstract "Sixteen flavonoids and their derivatives isolated from Desmos spp. were evaluated for inhibition of HIV replication in H9 lymphocyte cells. 2-Methoxy-3-methyl-4,6-dihydroxy-5-(3'-hydroxy)cinnamoylbenzaldehyde (12) and lawinal (6) demonstrated potent anti-HIV activity with EC(50) values of 0.022 and 2.30 microg/mL and therapeutic indexes of 489 and 45.2, respectively. Compound 12 appears to be an excellent lead for further anti-HIV drug development." @default.
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- W2084077105 date "2003-05-01" @default.
- W2084077105 modified "2023-10-05" @default.
- W2084077105 title "Anti-AIDS agents 54. A potent anti-HIV chalcone and flavonoids from genus Desmos" @default.
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- W2084077105 doi "https://doi.org/10.1016/s0960-894x(03)00197-5" @default.
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