FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084124416> ?p ?o ?g. }

• W2084124416 endingPage "148" @default.
• W2084124416 startingPage "139" @default.
• W2084124416 abstract "The freeze tolerant wood frog Rana sylvatica was studied to determine the impact of the freezing and thawing of this frog on the activity of γ-glutamyltranspeptidase in the liver. On exposure to −2·5°C, for 1, 12 and 24 h, frogs were found to be cool, covered with ice crystals and frozen, respectively. Thawing for 24 h at 4°C recovered the frogs completely. A 45 per cent decrease in the liver weight: body weight ratio was notable after 1 h at −2·5°C, suggestive of an early hepatic capacitance response. A glycemic response to freezing was observed: blood glucose levels exhibited a 55 per cent decrease after 1 h at −2·5°C on cooling; a 10·5-fold increase after 12 h at −2·5°C on the initiation of freezing; and a 22-fold increase after 24 h at −2·5°C in the fully frozen state. Blood glucose levels remained elevated four-fold in the thawed state. Plasma insulin levels were increased twofold in the frozen state and 1·8-fold in the thawed state, while plasma ketone levels were increased 1·8-fold in the frozen state and 1·5-fold in the thawed state. Plasma total T3 levels were decreased by 22 per cent in the frozen state and normalized on thawing. In homogenates and plasma membranes isolated from the livers of Rana sylvatica, the activity of γ-glutamyltranspeptidase was found to be elevated at all stages of the freeze–thaw process. After 1, 12 and 24 h at −2·5°C, activities were increased 2·5-, 2·3-, 2·4-fold respectively in the homogenates and 2·5-, 2·2-, 2·4-fold respectively in the plasma membranes. After thawing, activities were still increased 1·9-fold in both homogenates and plasma membranes. In homogenates prepared from the kidneys of Rana sylvatica, the activity of γ-glutamyltranspeptidase was increased 1·4-fold after 1 h at −2·5°C after which it returned to normal. The role of thyroid hormone in producing the increase in γ-glutamyltranspeptidase in the liver of Rana sylvatica in response to freezing is discussed as is the significance of the enzyme increase in terms of hepatic cytoprotection and freeze tolerance." @default.
• W2084124416 created "2016-06-24" @default.
• W2084124416 creator A5054177190 @default.
• W2084124416 creator A5074785536 @default.
• W2084124416 date "1996-06-01" @default.
• W2084124416 modified "2023-10-15" @default.
• W2084124416 title "Characterization of γ-glutamyltranspeptidase in the liver of the frog: 3. Response to freezing and thawing in the freeze-tolerant wood frog<i>Rana sylvatica</i>" @default.
• W2084124416 cites W1775749144 @default.
• W2084124416 cites W1902458626 @default.
• W2084124416 cites W19146602 @default.
• W2084124416 cites W1969238814 @default.
• W2084124416 cites W1970902024 @default.
• W2084124416 cites W1977149452 @default.
• W2084124416 cites W1980014330 @default.
• W2084124416 cites W1983938859 @default.
• W2084124416 cites W1993155280 @default.
• W2084124416 cites W1996797445 @default.
• W2084124416 cites W2000329823 @default.
• W2084124416 cites W2019619772 @default.
• W2084124416 cites W2026402362 @default.
• W2084124416 cites W2027709144 @default.
• W2084124416 cites W2028324681 @default.
• W2084124416 cites W2033600094 @default.
• W2084124416 cites W2040911557 @default.
• W2084124416 cites W2043643409 @default.
• W2084124416 cites W2053527204 @default.
• W2084124416 cites W2059522525 @default.
• W2084124416 cites W2072512235 @default.
• W2084124416 cites W2081064970 @default.
• W2084124416 cites W2089474990 @default.
• W2084124416 cites W2095083244 @default.
• W2084124416 cites W2116888647 @default.
• W2084124416 cites W2140047977 @default.
• W2084124416 cites W2147805226 @default.
• W2084124416 cites W2217133056 @default.
• W2084124416 cites W2316382488 @default.
• W2084124416 cites W4242870933 @default.
• W2084124416 cites W62898540 @default.
• W2084124416 doi "https://doi.org/10.1002/cbf.661" @default.
• W2084124416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8640954" @default.
• W2084124416 hasPublicationYear "1996" @default.
• W2084124416 type Work @default.
• W2084124416 sameAs 2084124416 @default.
• W2084124416 citedByCount "9" @default.
• W2084124416 countsByYear W20841244162015 @default.
• W2084124416 countsByYear W20841244162016 @default.
• W2084124416 countsByYear W20841244162018 @default.
• W2084124416 countsByYear W20841244162021 @default.
• W2084124416 crossrefType "journal-article" @default.
• W2084124416 hasAuthorship W2084124416A5054177190 @default.
• W2084124416 hasAuthorship W2084124416A5074785536 @default.
• W2084124416 hasConcept C126322002 @default.
• W2084124416 hasConcept C134018914 @default.
• W2084124416 hasConcept C140793950 @default.
• W2084124416 hasConcept C185592680 @default.
• W2084124416 hasConcept C2780881558 @default.
• W2084124416 hasConcept C43617362 @default.
• W2084124416 hasConcept C55493867 @default.
• W2084124416 hasConcept C71924100 @default.
• W2084124416 hasConcept C86803240 @default.
• W2084124416 hasConceptScore W2084124416C126322002 @default.
• W2084124416 hasConceptScore W2084124416C134018914 @default.
• W2084124416 hasConceptScore W2084124416C140793950 @default.
• W2084124416 hasConceptScore W2084124416C185592680 @default.
• W2084124416 hasConceptScore W2084124416C2780881558 @default.
• W2084124416 hasConceptScore W2084124416C43617362 @default.
• W2084124416 hasConceptScore W2084124416C55493867 @default.
• W2084124416 hasConceptScore W2084124416C71924100 @default.
• W2084124416 hasConceptScore W2084124416C86803240 @default.
• W2084124416 hasIssue "2" @default.
• W2084124416 hasLocation W20841244161 @default.
• W2084124416 hasLocation W20841244162 @default.
• W2084124416 hasOpenAccess W2084124416 @default.
• W2084124416 hasPrimaryLocation W20841244161 @default.
• W2084124416 hasRelatedWork W1939047279 @default.
• W2084124416 hasRelatedWork W199935210 @default.
• W2084124416 hasRelatedWork W2041489538 @default.
• W2084124416 hasRelatedWork W2059520724 @default.
• W2084124416 hasRelatedWork W2067293160 @default.
• W2084124416 hasRelatedWork W2350941306 @default.
• W2084124416 hasRelatedWork W2386553017 @default.
• W2084124416 hasRelatedWork W2415145529 @default.
• W2084124416 hasRelatedWork W2748952813 @default.
• W2084124416 hasRelatedWork W989046742 @default.
• W2084124416 hasVolume "14" @default.
• W2084124416 isParatext "false" @default.
• W2084124416 isRetracted "false" @default.
• W2084124416 magId "2084124416" @default.
• W2084124416 workType "article" @default.