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• W2084160112 abstract "Exercise alone or in combination with environmental heat stress can elevate blood S-100beta protein concentrations. However, the explanatory power of exercise with marked environmental heat stress on the appearance of S-100beta is questionable. It is possible that the process of heat acclimation might afford additional insight.Determine the S-100beta response to moderate-intensity exercise with heat strain before and after heat acclimation.Nine healthy male volunteers completed 10 consecutive days of heat acclimation consisting of up to 100 min of treadmill walking (1.56 m x s(-1), 4% grade) in the heat (45 degrees C, 20% relative humidity). Changes in HR, rectal temperature (T(re)), and sweat rate (SR) were examined to determine successful acclimation. Area under the curve (AUC) for T(re) greater than 38.5 degrees C was calculated to assess cumulative hyperthermia. Blood samples were taken before and after exercise on days 1 and 10 and were analyzed for serum osmolality and S-100beta concentration.All subjects displayed physiological adaptations to heat acclimation including a significant (P < 0.05) reduction in final HR (161 to 145 bpm) and T(re) (39.0 to 38.4 degrees C), as well as a modest (approximately 10%) increase in SR (1.10 to 1.20 L x h(-1); P = 0.09). No differences were observed in pre- to postexercise serum S-100beta concentrations on day 1 or 10, and no differences were observed in S-100beta values between days 1 and 10. No significant correlations were found between S-100beta values and any variable of interest.S-100beta concentrations do not necessarily increase in response to exercise-heat strain, and no effect of heat acclimation on S-100beta could be observed despite other quantifiable physiological adaptations." @default.
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• W2084160112 date "2008-08-01" @default.
• W2084160112 modified "2023-10-15" @default.
• W2084160112 title "Serum S-100β Response to Exercise-Heat Strain before and after Acclimation" @default.
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• W2084160112 doi "https://doi.org/10.1249/mss.0b013e31816d65a5" @default.
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