FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2084162854> ?p ?o ?g. }

• W2084162854 endingPage "48" @default.
• W2084162854 startingPage "35" @default.
• W2084162854 abstract "Polyporus umbellatus (Pers.) Fries (Polyporaceae, Zhuling ) has been commonly used in medicine for a wide range of ailments related to the edema, scanty urine, vaginal discharge, urinary dysfunction, as well as jaundice and diarrhea. The present paper reviewed the traditional uses, propagation, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus. All the available information on Polyporus umbellatus was collected via a library and electronic search (using Web of Science, Pubmed, ScienceDirect, Splinker, Google Scholar, etc.). Phytochemical studies showed the presence of many valuable secondary metabolites such as steroids, polysaccharides, anthraquinones and nucleosides. Crude extracts and isolated compounds showed a wide spectrum of pharmacological activities including diuretic, nephroprotective, anti-cancer, immuno-enhancing, hepatoprotective, anti-inflammatory and antioxidative activities. The pharmacokinetic studies demonstrated that the ergosterol and ergone had a high distribution and absorption in the plasma and the two main components of Polyporus umbellatus were mainly excreted by faeces. The determination of multiple chemical components was successfully applied to the quality control of Polyporus umbellatus. Modern phytochemical, pharmacological and metabonomic investigations showed that the crude extracts and isolated compounds from Polyporus umbellatus possess many kinds of biological functions, especially in the diuretic activities and the treatment of kidney diseases as well as anti-cancer, immuno-enhancing and hepatoprotective activities. The pathways of the distribution, absorption, metabolism and excretion of main steroidal compounds were clarified by pharmacokinetic studies. Most of the pharmacological studies were conducted using crude and poorly characterized extracts of Polyporus umbellatus in animals especially in case of diuretic activities and the treatment of kidney diseases. Thus, more bioactive components especially diuretic compounds should be identified using bioactivity-guided isolation strategies and the possible mechanism of action as well as potential synergistic or antagonistic effects of multi-component mixtures derived from Polyporus umbellatus need to be evaluated integrating pharmacological, pharmacokinetic, bioavailability-centered and physiological approaches. In addition, more experiments including in vitro, in vivo and clinical studies should be encouraged to identify any side effects or toxicity. These achievements will further expand the existing therapeutic potential of Polyporus umbellatus and provide a beneficial support to its future further clinical use in modern medicine." @default.
• W2084162854 created "2016-06-24" @default.
• W2084162854 creator A5043016170 @default.
• W2084162854 date "2013-08-01" @default.
• W2084162854 modified "2023-10-16" @default.
• W2084162854 title "Traditional uses, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus (Pers.) Fries: A review" @default.
• W2084162854 cites W1551009260 @default.
• W2084162854 cites W1967634179 @default.
• W2084162854 cites W1967975046 @default.
• W2084162854 cites W1969746343 @default.
• W2084162854 cites W1976031027 @default.
• W2084162854 cites W1980481877 @default.
• W2084162854 cites W1981424852 @default.
• W2084162854 cites W1982407010 @default.
• W2084162854 cites W1983857109 @default.
• W2084162854 cites W1992625181 @default.
• W2084162854 cites W1998411915 @default.
• W2084162854 cites W2000534561 @default.
• W2084162854 cites W2001770723 @default.
• W2084162854 cites W2007658005 @default.
• W2084162854 cites W2009745420 @default.
• W2084162854 cites W2011466037 @default.
• W2084162854 cites W2014992737 @default.
• W2084162854 cites W2016073926 @default.
• W2084162854 cites W2016700929 @default.
• W2084162854 cites W2017104472 @default.
• W2084162854 cites W2019621079 @default.
• W2084162854 cites W2019800682 @default.
• W2084162854 cites W2020623141 @default.
• W2084162854 cites W2025094444 @default.
• W2084162854 cites W2025673020 @default.
• W2084162854 cites W2025930235 @default.
• W2084162854 cites W2026582325 @default.
• W2084162854 cites W2031188965 @default.
• W2084162854 cites W2036613336 @default.
• W2084162854 cites W2042067955 @default.
• W2084162854 cites W2043269350 @default.
• W2084162854 cites W2047735358 @default.
• W2084162854 cites W2049739158 @default.
• W2084162854 cites W2052243782 @default.
• W2084162854 cites W2057243906 @default.
• W2084162854 cites W2057824539 @default.
• W2084162854 cites W2057932524 @default.
• W2084162854 cites W2062050257 @default.
• W2084162854 cites W2064909068 @default.
• W2084162854 cites W2065672265 @default.
• W2084162854 cites W2065710264 @default.
• W2084162854 cites W2067120810 @default.
• W2084162854 cites W2067218262 @default.
• W2084162854 cites W2068087618 @default.
• W2084162854 cites W2072291431 @default.
• W2084162854 cites W2080110586 @default.
• W2084162854 cites W2081180901 @default.
• W2084162854 cites W2081620729 @default.
• W2084162854 cites W2082611277 @default.
• W2084162854 cites W2084013581 @default.
• W2084162854 cites W2085193821 @default.
• W2084162854 cites W2085977005 @default.
• W2084162854 cites W2086637979 @default.
• W2084162854 cites W2087374017 @default.
• W2084162854 cites W2089237173 @default.
• W2084162854 cites W2093367654 @default.
• W2084162854 cites W2093868208 @default.
• W2084162854 cites W2097169397 @default.
• W2084162854 cites W2109852950 @default.
• W2084162854 cites W2121954494 @default.
• W2084162854 cites W2126338266 @default.
• W2084162854 cites W2126450351 @default.
• W2084162854 cites W2128067447 @default.
• W2084162854 cites W2138855117 @default.
• W2084162854 cites W2140355390 @default.
• W2084162854 cites W2140999445 @default.
• W2084162854 cites W2157299203 @default.
• W2084162854 cites W2163587286 @default.
• W2084162854 cites W2164487041 @default.
• W2084162854 cites W2316444709 @default.
• W2084162854 cites W2321873060 @default.
• W2084162854 cites W2395276638 @default.
• W2084162854 cites W2432380451 @default.
• W2084162854 cites W254227334 @default.
• W2084162854 cites W3028025344 @default.
• W2084162854 doi "https://doi.org/10.1016/j.jep.2013.06.031" @default.
• W2084162854 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23811047" @default.
• W2084162854 hasPublicationYear "2013" @default.
• W2084162854 type Work @default.
• W2084162854 sameAs 2084162854 @default.
• W2084162854 citedByCount "88" @default.
• W2084162854 countsByYear W20841628542014 @default.
• W2084162854 countsByYear W20841628542015 @default.
• W2084162854 countsByYear W20841628542016 @default.
• W2084162854 countsByYear W20841628542017 @default.
• W2084162854 countsByYear W20841628542018 @default.
• W2084162854 countsByYear W20841628542019 @default.
• W2084162854 countsByYear W20841628542020 @default.
• W2084162854 countsByYear W20841628542021 @default.
• W2084162854 countsByYear W20841628542022 @default.
• W2084162854 countsByYear W20841628542023 @default.
• W2084162854 crossrefType "journal-article" @default.

• next