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• W2084228927 endingPage "490" @default.
• W2084228927 startingPage "477" @default.
• W2084228927 abstract "Developmental dyslexia can be distinguished as different cognitive subtypes with and without phonological deficits. However, despite some general agreement on the neurobiological basis of dyslexia, the neurofunctional mechanisms underlying these cognitive subtypes remain to be identified. The present BOLD fMRI study thus aimed at investigating by which distinct and/or shared neural activation patterns dyslexia subtypes are characterized. German dyslexic fourth graders with and without deficits in phonological awareness and age-matched normal readers performed a phonological decision task: does the auditory word contain the phoneme/a/? Both dyslexic subtypes showed increased activation in the right cerebellum (Lobule IV) compared to controls. Subtype-specific increased activation was systematically found for the phonological dyslexics as compared to those without this deficit and controls in the left inferior frontal gyrus (area 44: phonological segmentation), the left SMA (area 6), the left precentral gyrus (area 6) and the right insula. Non-phonological dyslexics revealed subtype-specific increased activation in the left supramarginal gyrus (area PFcm; phonological storage) and angular gyrus (area PGp). The study thus provides the first direct evidence for the neurobiological grounding of dyslexia subtypes. Moreover, the data contribute to a better understanding of the frequently encountered heterogeneous neuroimaging results in the field of dyslexia." @default.
• W2084228927 created "2016-06-24" @default.
• W2084228927 creator A5002820724 @default.
• W2084228927 creator A5003289976 @default.
• W2084228927 creator A5007328456 @default.
• W2084228927 creator A5039690445 @default.
• W2084228927 creator A5079396980 @default.
• W2084228927 date "2013-01-01" @default.
• W2084228927 modified "2023-09-26" @default.
• W2084228927 title "Distinct neural signatures of cognitive subtypes of dyslexia with and without phonological deficits" @default.
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